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Characterization and Pharmacokinetic Evaluation of Oxaliplatin Long-Circulating Liposomes

The clinical efficacy of Oxaliplatin (L-OHP) is potentially limited by dose-dependent neurotoxicity and high partitioning to erythrocytes in vivo. Long-circulating liposomes could improve the pharmacokinetic profile of L-OHP and thus enhance its therapeutic efficacy and reduce its toxicity. The purp...

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Detalles Bibliográficos
Autores principales:	Cheraga, Nihad, Ouahab, Ammar, Shen, Yan, Huang, Ning-Ping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8079196/ https://www.ncbi.nlm.nih.gov/pubmed/33987441 http://dx.doi.org/10.1155/2021/5949804

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