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Effect of photobiomodulation therapy on painful temporomandibular disorders

To evaluate the effect of photobiomodulation therapy (PBMT) on painful temporomandibular disorders (TMD) patients in a randomized, double-blinded, placebo-controlled manner. Participants were divided into a masseter myalgia group (n = 88) and a temporomandibular joint (TMJ) arthralgia group (n = 87)...

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Autores principales: Aisaiti, Adila, Zhou, Yanli, Wen, Yue, Zhou, Weina, Wang, Chen, Zhao, Jing, Yu, Linfeng, Zhang, Jinglu, Wang, Kelun, Svensson, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8079391/
https://www.ncbi.nlm.nih.gov/pubmed/33907210
http://dx.doi.org/10.1038/s41598-021-87265-0
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author Aisaiti, Adila
Zhou, Yanli
Wen, Yue
Zhou, Weina
Wang, Chen
Zhao, Jing
Yu, Linfeng
Zhang, Jinglu
Wang, Kelun
Svensson, Peter
author_facet Aisaiti, Adila
Zhou, Yanli
Wen, Yue
Zhou, Weina
Wang, Chen
Zhao, Jing
Yu, Linfeng
Zhang, Jinglu
Wang, Kelun
Svensson, Peter
author_sort Aisaiti, Adila
collection PubMed
description To evaluate the effect of photobiomodulation therapy (PBMT) on painful temporomandibular disorders (TMD) patients in a randomized, double-blinded, placebo-controlled manner. Participants were divided into a masseter myalgia group (n = 88) and a temporomandibular joint (TMJ) arthralgia group (n = 87) according to the Diagnostic Criteria for Temporomandibular Disorders (DC/TMD). Both groups randomly received PBMT or placebo treatment once a day for 7 consecutive days, one session. The PBMT was applied with a gallium-aluminum-arsenide (GaAlAs) laser (wavelength = 810 nm) at pre-determined points in the masseter muscle (6 J/cm(2), 3 regions, 60 s) or TMJ region (6 J/cm(2), 5 points, 30 s) according to their most painful site. Pain intensity was rated on a 0–10 numerical rating scale (NRS) and pressure pain thresholds (PPT) and mechanical sensitivity mapping were recorded before and after the treatment on day 1 and day 7. Jaw function was assessed by pain free jaw opening, maximum unassisted jaw opening, maximum assisted jaw opening, maximum protrusion and right and left excursion. Data were analyzed with a mixed model analysis of variance (ANOVA). Pain intensity in arthralgia patients decreased over time (P < 0.001) for both types of interventions, however, PBMT caused greater reduction in pain scores than placebo (P = 0.014). For myalgia patients, pain intensity decreased over time (P < 0.001) but without difference between interventions (P = 0.074). PPTs increased in both myalgia (P < 0.001) and TMJ arthralgia patients over time (P < 0.001) but without difference between interventions (P ≥ 0.614). Overall, PBMT was associated with marginally better improvements in range of motion compared to placebo in both myalgia and arthralgia patients. Pain intensity, sensory function and jaw movements improve after both PBMT and placebo treatments in myalgia and arthralgia patients indicating a substantial non-specific effect of PBMT.
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spelling pubmed-80793912021-04-28 Effect of photobiomodulation therapy on painful temporomandibular disorders Aisaiti, Adila Zhou, Yanli Wen, Yue Zhou, Weina Wang, Chen Zhao, Jing Yu, Linfeng Zhang, Jinglu Wang, Kelun Svensson, Peter Sci Rep Article To evaluate the effect of photobiomodulation therapy (PBMT) on painful temporomandibular disorders (TMD) patients in a randomized, double-blinded, placebo-controlled manner. Participants were divided into a masseter myalgia group (n = 88) and a temporomandibular joint (TMJ) arthralgia group (n = 87) according to the Diagnostic Criteria for Temporomandibular Disorders (DC/TMD). Both groups randomly received PBMT or placebo treatment once a day for 7 consecutive days, one session. The PBMT was applied with a gallium-aluminum-arsenide (GaAlAs) laser (wavelength = 810 nm) at pre-determined points in the masseter muscle (6 J/cm(2), 3 regions, 60 s) or TMJ region (6 J/cm(2), 5 points, 30 s) according to their most painful site. Pain intensity was rated on a 0–10 numerical rating scale (NRS) and pressure pain thresholds (PPT) and mechanical sensitivity mapping were recorded before and after the treatment on day 1 and day 7. Jaw function was assessed by pain free jaw opening, maximum unassisted jaw opening, maximum assisted jaw opening, maximum protrusion and right and left excursion. Data were analyzed with a mixed model analysis of variance (ANOVA). Pain intensity in arthralgia patients decreased over time (P < 0.001) for both types of interventions, however, PBMT caused greater reduction in pain scores than placebo (P = 0.014). For myalgia patients, pain intensity decreased over time (P < 0.001) but without difference between interventions (P = 0.074). PPTs increased in both myalgia (P < 0.001) and TMJ arthralgia patients over time (P < 0.001) but without difference between interventions (P ≥ 0.614). Overall, PBMT was associated with marginally better improvements in range of motion compared to placebo in both myalgia and arthralgia patients. Pain intensity, sensory function and jaw movements improve after both PBMT and placebo treatments in myalgia and arthralgia patients indicating a substantial non-specific effect of PBMT. Nature Publishing Group UK 2021-04-27 /pmc/articles/PMC8079391/ /pubmed/33907210 http://dx.doi.org/10.1038/s41598-021-87265-0 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Aisaiti, Adila
Zhou, Yanli
Wen, Yue
Zhou, Weina
Wang, Chen
Zhao, Jing
Yu, Linfeng
Zhang, Jinglu
Wang, Kelun
Svensson, Peter
Effect of photobiomodulation therapy on painful temporomandibular disorders
title Effect of photobiomodulation therapy on painful temporomandibular disorders
title_full Effect of photobiomodulation therapy on painful temporomandibular disorders
title_fullStr Effect of photobiomodulation therapy on painful temporomandibular disorders
title_full_unstemmed Effect of photobiomodulation therapy on painful temporomandibular disorders
title_short Effect of photobiomodulation therapy on painful temporomandibular disorders
title_sort effect of photobiomodulation therapy on painful temporomandibular disorders
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8079391/
https://www.ncbi.nlm.nih.gov/pubmed/33907210
http://dx.doi.org/10.1038/s41598-021-87265-0
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