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PTEN is a predictive biomarker of trastuzumab resistance and prognostic factor in HER2-overexpressing gastroesophageal adenocarcinoma

Poor trastuzumab (Tmab) response of patients with human epidermal growth factor receptor 2-overexpressing gastric or gastroesophageal junction adenocarcinoma (HER2-GEA) is associated with the inhibition of phosphatase and tensin homolog (PTEN) expression. In this multicenter, retrospective observati...

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Detalles Bibliográficos
Autores principales:	Yokoyama, Daiju, Hisamori, Shigeo, Deguchi, Yasunori, Nishigori, Tatsuto, Okabe, Hiroshi, Kanaya, Seiichiro, Manaka, Dai, Kadokawa, Yoshio, Hata, Hiroaki, Minamiguchi, Sachiko, Tsunoda, Shigeru, Obama, Kazutaka, Sakai, Yoshiharu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8079403/ https://www.ncbi.nlm.nih.gov/pubmed/33907203 http://dx.doi.org/10.1038/s41598-021-88331-3

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