Cargando…

Preoperative stroke before cardiac surgery does not increase risk of postoperative stroke

The optimal time when surgery can be safely performed after stroke is unknown. The purpose of this study was to investigate how cardiac surgery timing after stroke impacts postoperative outcomes between 2011–2017 were reviewed. Variables were extracted from the institutional Society of Thoracic Surg...

Descripción completa

Detalles Bibliográficos
Autores principales: Matthews, Caleb R., Hartman, Timothy, Madison, Mackenzie, Villelli, Nicolas W., Namburi, Niharika, Colgate, Cameron L., Faiza, Zainab, Lee, Lawrence S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8079406/
https://www.ncbi.nlm.nih.gov/pubmed/33907259
http://dx.doi.org/10.1038/s41598-021-88441-y
_version_ 1783685223257473024
author Matthews, Caleb R.
Hartman, Timothy
Madison, Mackenzie
Villelli, Nicolas W.
Namburi, Niharika
Colgate, Cameron L.
Faiza, Zainab
Lee, Lawrence S.
author_facet Matthews, Caleb R.
Hartman, Timothy
Madison, Mackenzie
Villelli, Nicolas W.
Namburi, Niharika
Colgate, Cameron L.
Faiza, Zainab
Lee, Lawrence S.
author_sort Matthews, Caleb R.
collection PubMed
description The optimal time when surgery can be safely performed after stroke is unknown. The purpose of this study was to investigate how cardiac surgery timing after stroke impacts postoperative outcomes between 2011–2017 were reviewed. Variables were extracted from the institutional Society of Thoracic Surgeons database, statewide patient registry, and medical records. Subjects were classified based upon presence of endocarditis and further grouped by timing of preoperative stroke relative to cardiac surgery: Recent (stroke within two weeks before surgery), Intermediate (between two and six weeks before), and Remote (greater than six weeks before). Postoperative outcomes were compared amongst groups. 157 patients were included: 54 in endocarditis and 103 in non-endocarditis, with 47 in Recent, 26 in Intermediate, and 84 in Remote. 30-day mortality and postoperative stroke rate were similar across the three subgroups for both endocarditis and non-endocarditis. Of patients with postoperative stroke, mortality was 30% (95% CI 4.6–66). Timing of cardiac surgery after stroke occurrence does not seem to affect postoperative stroke or mortality. If postoperative stroke does occur, subsequent stroke-related mortality is high.
format Online
Article
Text
id pubmed-8079406
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Nature Publishing Group UK
record_format MEDLINE/PubMed
spelling pubmed-80794062021-04-28 Preoperative stroke before cardiac surgery does not increase risk of postoperative stroke Matthews, Caleb R. Hartman, Timothy Madison, Mackenzie Villelli, Nicolas W. Namburi, Niharika Colgate, Cameron L. Faiza, Zainab Lee, Lawrence S. Sci Rep Article The optimal time when surgery can be safely performed after stroke is unknown. The purpose of this study was to investigate how cardiac surgery timing after stroke impacts postoperative outcomes between 2011–2017 were reviewed. Variables were extracted from the institutional Society of Thoracic Surgeons database, statewide patient registry, and medical records. Subjects were classified based upon presence of endocarditis and further grouped by timing of preoperative stroke relative to cardiac surgery: Recent (stroke within two weeks before surgery), Intermediate (between two and six weeks before), and Remote (greater than six weeks before). Postoperative outcomes were compared amongst groups. 157 patients were included: 54 in endocarditis and 103 in non-endocarditis, with 47 in Recent, 26 in Intermediate, and 84 in Remote. 30-day mortality and postoperative stroke rate were similar across the three subgroups for both endocarditis and non-endocarditis. Of patients with postoperative stroke, mortality was 30% (95% CI 4.6–66). Timing of cardiac surgery after stroke occurrence does not seem to affect postoperative stroke or mortality. If postoperative stroke does occur, subsequent stroke-related mortality is high. Nature Publishing Group UK 2021-04-27 /pmc/articles/PMC8079406/ /pubmed/33907259 http://dx.doi.org/10.1038/s41598-021-88441-y Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Matthews, Caleb R.
Hartman, Timothy
Madison, Mackenzie
Villelli, Nicolas W.
Namburi, Niharika
Colgate, Cameron L.
Faiza, Zainab
Lee, Lawrence S.
Preoperative stroke before cardiac surgery does not increase risk of postoperative stroke
title Preoperative stroke before cardiac surgery does not increase risk of postoperative stroke
title_full Preoperative stroke before cardiac surgery does not increase risk of postoperative stroke
title_fullStr Preoperative stroke before cardiac surgery does not increase risk of postoperative stroke
title_full_unstemmed Preoperative stroke before cardiac surgery does not increase risk of postoperative stroke
title_short Preoperative stroke before cardiac surgery does not increase risk of postoperative stroke
title_sort preoperative stroke before cardiac surgery does not increase risk of postoperative stroke
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8079406/
https://www.ncbi.nlm.nih.gov/pubmed/33907259
http://dx.doi.org/10.1038/s41598-021-88441-y
work_keys_str_mv AT matthewscalebr preoperativestrokebeforecardiacsurgerydoesnotincreaseriskofpostoperativestroke
AT hartmantimothy preoperativestrokebeforecardiacsurgerydoesnotincreaseriskofpostoperativestroke
AT madisonmackenzie preoperativestrokebeforecardiacsurgerydoesnotincreaseriskofpostoperativestroke
AT villellinicolasw preoperativestrokebeforecardiacsurgerydoesnotincreaseriskofpostoperativestroke
AT namburiniharika preoperativestrokebeforecardiacsurgerydoesnotincreaseriskofpostoperativestroke
AT colgatecameronl preoperativestrokebeforecardiacsurgerydoesnotincreaseriskofpostoperativestroke
AT faizazainab preoperativestrokebeforecardiacsurgerydoesnotincreaseriskofpostoperativestroke
AT leelawrences preoperativestrokebeforecardiacsurgerydoesnotincreaseriskofpostoperativestroke