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Periplasmic synthesis and purification of the human prolactin antagonist Δ(1-11)-G129R-hPRL
The human prolactin antagonist Δ(1-11)-G129R-hPRL is a 21.9 kDa recombinant protein with 188 amino acids that downregulates the proliferation of a variety of cells expressing prolactin receptors. Periplasmic expression of recombinant proteins in E. coli has been considered an option for obtaining a...
Autores principales: | Suzuki, Miriam F., Almeida, Larissa A., Pomin, Stephanie A., Silva, Felipe D., Freire, Renan P., Oliveira, João E., Affonso, Regina, Soares, Carlos R. J., Bartolini, Paolo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8079533/ https://www.ncbi.nlm.nih.gov/pubmed/33905023 http://dx.doi.org/10.1186/s13568-021-01209-5 |
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