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Combining electrophysiology and optogenetics for functional screening of pyramidal neurons in the mouse prefrontal cortex
Here, we present a comprehensive protocol to analyze the roles of disease-related genes in synaptic transmission. We have developed a pipeline of electrophysiological techniques and combined these with optogenetics in the medial prefrontal cortex of mice. This methodology provides a cost-effective,...
Autores principales: | Nagahama, Kenichiro, Fujino, Shuhei, Watanabe, Takaki, Uesaka, Naofumi, Kano, Masanobu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8079664/ https://www.ncbi.nlm.nih.gov/pubmed/33937875 http://dx.doi.org/10.1016/j.xpro.2021.100469 |
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