Phospho-Site Mutations in Transcription Factor Suppressor of Hairless Impact Notch Signaling Activity During Hematopoiesis in Drosophila

The highly conserved Notch signaling pathway controls a multitude of developmental processes including hematopoiesis. Here, we provide evidence for a novel mechanism of tissue-specific Notch regulation involving phosphorylation of CSL transcription factors within the DNA-binding domain. Earlier we f...

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Detalles Bibliográficos
Autores principales: Frankenreiter, Lisa, Gahr, Bernd M., Schmid, Hannes, Zimmermann, Mirjam, Deichsel, Sebastian, Hoffmeister, Philipp, Turkiewicz, Aleksandra, Borggrefe, Tilman, Oswald, Franz, Nagel, Anja C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8079769/
https://www.ncbi.nlm.nih.gov/pubmed/33937259
http://dx.doi.org/10.3389/fcell.2021.658820

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8079769/
https://www.ncbi.nlm.nih.gov/pubmed/33937259
http://dx.doi.org/10.3389/fcell.2021.658820

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