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Peripheral TIGIT+ T Follicular Helper Cells That Produce High Levels of Interleukin-21 via OX40 Represent Disease Activity in IgG4-Related Disease

OBJECTIVES: Multiple studies suggest that interleukin (IL)-21 plays a pivotal role in the differentiation of B cells and activation of cytotoxic T cells and is involved in the pathogenesis of IgG4-related disease (IgG4-RD). T cell immunoreceptor with immunoglobulin and ITIM domain (TIGIT) is a new m...

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Detalles Bibliográficos
Autores principales:	Akiyama, Mitsuhiro, Suzuki, Katsuya, Yoshimoto, Keiko, Yasuoka, Hidekata, Kaneko, Yuko, Takeuchi, Tsutomu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8079782/ https://www.ncbi.nlm.nih.gov/pubmed/33936071 http://dx.doi.org/10.3389/fimmu.2021.651357

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