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Heuristic-based allocation of supply constrained blood platelets in emerging economies
Platelets are valuable, but highly perishable, blood components used in the treatment of, among others, viral dengue fever, blood-related illness, and post-chemotherapy following cancer. Given the short shelf-life of 3–5 days and a highly volatile supply and demand pattern, platelet inventory alloca...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8079886/ http://dx.doi.org/10.1007/s10732-021-09474-0 |
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author | Ødegaard, Fredrik Roy, Sudipendra Nath |
author_facet | Ødegaard, Fredrik Roy, Sudipendra Nath |
author_sort | Ødegaard, Fredrik |
collection | PubMed |
description | Platelets are valuable, but highly perishable, blood components used in the treatment of, among others, viral dengue fever, blood-related illness, and post-chemotherapy following cancer. Given the short shelf-life of 3–5 days and a highly volatile supply and demand pattern, platelet inventory allocation is a challenging task. This is especially prevalent in emerging economies where demand variability is more pronounced due to neglected tropical diseases, and a perpetual shortage of supply. The consequences of which have given rise to an illegal ‘red market’. Motivated by experience at a regional hospital in India, we investigate the problem of platelet allocation among three priority-differentiated demand streams. Specifically we consider a central hospital which, in addition to internal emergency and non-emergency requests, faces external demand from local clinics. We analyze the platelet allocation decision from a social planner’s perspective and propose an allocation heuristic based on revenue management (RM) principles. The objective is to maximize total social benefit in a highly supply-constrained environment. Using data from the aforementioned Indian hospital as a case study, we conduct a numerical simulation and sensitivity analysis to evaluate the allocation heuristic. The performance of the RM-based policy is evaluated against the current sequential first come, first serve policy and two fixed proportion-based rationing policies. It is shown that the RM-based policy overall dominates, serves patients with the highest medical urgency better, and can curtail patients’ need to procure platelets from commercial sources. |
format | Online Article Text |
id | pubmed-8079886 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Springer US |
record_format | MEDLINE/PubMed |
spelling | pubmed-80798862021-04-28 Heuristic-based allocation of supply constrained blood platelets in emerging economies Ødegaard, Fredrik Roy, Sudipendra Nath J Heuristics Article Platelets are valuable, but highly perishable, blood components used in the treatment of, among others, viral dengue fever, blood-related illness, and post-chemotherapy following cancer. Given the short shelf-life of 3–5 days and a highly volatile supply and demand pattern, platelet inventory allocation is a challenging task. This is especially prevalent in emerging economies where demand variability is more pronounced due to neglected tropical diseases, and a perpetual shortage of supply. The consequences of which have given rise to an illegal ‘red market’. Motivated by experience at a regional hospital in India, we investigate the problem of platelet allocation among three priority-differentiated demand streams. Specifically we consider a central hospital which, in addition to internal emergency and non-emergency requests, faces external demand from local clinics. We analyze the platelet allocation decision from a social planner’s perspective and propose an allocation heuristic based on revenue management (RM) principles. The objective is to maximize total social benefit in a highly supply-constrained environment. Using data from the aforementioned Indian hospital as a case study, we conduct a numerical simulation and sensitivity analysis to evaluate the allocation heuristic. The performance of the RM-based policy is evaluated against the current sequential first come, first serve policy and two fixed proportion-based rationing policies. It is shown that the RM-based policy overall dominates, serves patients with the highest medical urgency better, and can curtail patients’ need to procure platelets from commercial sources. Springer US 2021-04-28 2021 /pmc/articles/PMC8079886/ http://dx.doi.org/10.1007/s10732-021-09474-0 Text en © The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2021 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic. |
spellingShingle | Article Ødegaard, Fredrik Roy, Sudipendra Nath Heuristic-based allocation of supply constrained blood platelets in emerging economies |
title | Heuristic-based allocation of supply constrained blood platelets in emerging economies |
title_full | Heuristic-based allocation of supply constrained blood platelets in emerging economies |
title_fullStr | Heuristic-based allocation of supply constrained blood platelets in emerging economies |
title_full_unstemmed | Heuristic-based allocation of supply constrained blood platelets in emerging economies |
title_short | Heuristic-based allocation of supply constrained blood platelets in emerging economies |
title_sort | heuristic-based allocation of supply constrained blood platelets in emerging economies |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8079886/ http://dx.doi.org/10.1007/s10732-021-09474-0 |
work_keys_str_mv | AT ødegaardfredrik heuristicbasedallocationofsupplyconstrainedbloodplateletsinemergingeconomies AT roysudipendranath heuristicbasedallocationofsupplyconstrainedbloodplateletsinemergingeconomies |