Gastric Hyperplastic Polyps after Argon Plasma Coagulation for Gastric Antral Vascular Ectasia in Patients with Liver Cirrhosis: A Case Suggesting the “Gastrin Link Theory”

We herein report a case of gastric hyperplastic polyps after argon plasma coagulation (APC) for gastric antral vascular ectasia (GAVE) in the antrum of a 65-year-old man with liver cirrhosis and hypergastrinemia induced by long-term proton pump inhibitor (PPI) use. Two years after APC therapy, endos...

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Autores principales: Nishino, Ken, Kawanaka, Miwa, Suehiro, Mitsuhiko, Yoshioka, Naoko, Nakamura, Jun, Urata, Noriyo, Tanigawa, Tomohiro, Sasai, Takako, Oka, Takahito, Monobe, Yasumasa, Saji, Yoshiaki, Kawamoto, Hirofumi, Haruma, Ken
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8079916/
https://www.ncbi.nlm.nih.gov/pubmed/33116013
http://dx.doi.org/10.2169/internalmedicine.5837-20
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author Nishino, Ken
Kawanaka, Miwa
Suehiro, Mitsuhiko
Yoshioka, Naoko
Nakamura, Jun
Urata, Noriyo
Tanigawa, Tomohiro
Sasai, Takako
Oka, Takahito
Monobe, Yasumasa
Saji, Yoshiaki
Kawamoto, Hirofumi
Haruma, Ken
author_facet Nishino, Ken
Kawanaka, Miwa
Suehiro, Mitsuhiko
Yoshioka, Naoko
Nakamura, Jun
Urata, Noriyo
Tanigawa, Tomohiro
Sasai, Takako
Oka, Takahito
Monobe, Yasumasa
Saji, Yoshiaki
Kawamoto, Hirofumi
Haruma, Ken
author_sort Nishino, Ken
collection PubMed
description We herein report a case of gastric hyperplastic polyps after argon plasma coagulation (APC) for gastric antral vascular ectasia (GAVE) in the antrum of a 65-year-old man with liver cirrhosis and hypergastrinemia induced by long-term proton pump inhibitor (PPI) use. Two years after APC therapy, endoscopy demonstrated multiple gastric polyps in the antrum and angle. A gastric polyp biopsy indicated foveolar epithelium hyperplasia, which was diagnosed as gastric hyperplastic polyps. One year after switching to an H2 blocker antagonist, endoscopy revealed that the polyps and GAVE had disappeared, with normal gastrin levels suggesting that PPI-induced hypergastrinemia had caused gastric hyperplastic polyps after APC therapy, and the polyps had disappeared after discontinuing PPIs.
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spelling pubmed-80799162021-05-11 Gastric Hyperplastic Polyps after Argon Plasma Coagulation for Gastric Antral Vascular Ectasia in Patients with Liver Cirrhosis: A Case Suggesting the “Gastrin Link Theory” Nishino, Ken Kawanaka, Miwa Suehiro, Mitsuhiko Yoshioka, Naoko Nakamura, Jun Urata, Noriyo Tanigawa, Tomohiro Sasai, Takako Oka, Takahito Monobe, Yasumasa Saji, Yoshiaki Kawamoto, Hirofumi Haruma, Ken Intern Med Case Report We herein report a case of gastric hyperplastic polyps after argon plasma coagulation (APC) for gastric antral vascular ectasia (GAVE) in the antrum of a 65-year-old man with liver cirrhosis and hypergastrinemia induced by long-term proton pump inhibitor (PPI) use. Two years after APC therapy, endoscopy demonstrated multiple gastric polyps in the antrum and angle. A gastric polyp biopsy indicated foveolar epithelium hyperplasia, which was diagnosed as gastric hyperplastic polyps. One year after switching to an H2 blocker antagonist, endoscopy revealed that the polyps and GAVE had disappeared, with normal gastrin levels suggesting that PPI-induced hypergastrinemia had caused gastric hyperplastic polyps after APC therapy, and the polyps had disappeared after discontinuing PPIs. The Japanese Society of Internal Medicine 2020-10-28 2021-04-01 /pmc/articles/PMC8079916/ /pubmed/33116013 http://dx.doi.org/10.2169/internalmedicine.5837-20 Text en Copyright © 2021 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/The Internal Medicine is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Nishino, Ken
Kawanaka, Miwa
Suehiro, Mitsuhiko
Yoshioka, Naoko
Nakamura, Jun
Urata, Noriyo
Tanigawa, Tomohiro
Sasai, Takako
Oka, Takahito
Monobe, Yasumasa
Saji, Yoshiaki
Kawamoto, Hirofumi
Haruma, Ken
Gastric Hyperplastic Polyps after Argon Plasma Coagulation for Gastric Antral Vascular Ectasia in Patients with Liver Cirrhosis: A Case Suggesting the “Gastrin Link Theory”
title Gastric Hyperplastic Polyps after Argon Plasma Coagulation for Gastric Antral Vascular Ectasia in Patients with Liver Cirrhosis: A Case Suggesting the “Gastrin Link Theory”
title_full Gastric Hyperplastic Polyps after Argon Plasma Coagulation for Gastric Antral Vascular Ectasia in Patients with Liver Cirrhosis: A Case Suggesting the “Gastrin Link Theory”
title_fullStr Gastric Hyperplastic Polyps after Argon Plasma Coagulation for Gastric Antral Vascular Ectasia in Patients with Liver Cirrhosis: A Case Suggesting the “Gastrin Link Theory”
title_full_unstemmed Gastric Hyperplastic Polyps after Argon Plasma Coagulation for Gastric Antral Vascular Ectasia in Patients with Liver Cirrhosis: A Case Suggesting the “Gastrin Link Theory”
title_short Gastric Hyperplastic Polyps after Argon Plasma Coagulation for Gastric Antral Vascular Ectasia in Patients with Liver Cirrhosis: A Case Suggesting the “Gastrin Link Theory”
title_sort gastric hyperplastic polyps after argon plasma coagulation for gastric antral vascular ectasia in patients with liver cirrhosis: a case suggesting the “gastrin link theory”
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8079916/
https://www.ncbi.nlm.nih.gov/pubmed/33116013
http://dx.doi.org/10.2169/internalmedicine.5837-20
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