Cargando…
Targeting the Urotensin II/UT G Protein-Coupled Receptor to Counteract Angiogenesis and Mesenchymal Hypoxia/Necrosis in Glioblastoma
Glioblastomas (GBMs) are the most common primary brain tumors characterized by strong invasiveness and angiogenesis. GBM cells and microenvironment secrete angiogenic factors and also express chemoattractant G protein-coupled receptors (GPCRs) to their advantage. We investigated the role of the vaso...
Autores principales: | Le Joncour, Vadim, Guichet, Pierre-Olivier, Dembélé, Kleouforo-Paul, Mutel, Alexandre, Campisi, Daniele, Perzo, Nicolas, Desrues, Laurence, Modzelewski, Romain, Couraud, Pierre-Olivier, Honnorat, Jérôme, Ferracci, François-Xavier, Marguet, Florent, Laquerrière, Annie, Vera, Pierre, Bohn, Pierre, Langlois, Olivier, Morin, Fabrice, Gandolfo, Pierrick, Castel, Hélène |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8079989/ https://www.ncbi.nlm.nih.gov/pubmed/33937253 http://dx.doi.org/10.3389/fcell.2021.652544 |
Ejemplares similares
-
Development of Novel (111)-In-Labelled DOTA Urotensin II Analogues for Targeting the UT Receptor Overexpressed in Solid Tumours
por: Poret, Benjamin, et al.
Publicado: (2020) -
The core autophagy protein ATG9A controls dynamics of cell protrusions and directed migration
por: Campisi, Daniele, et al.
Publicado: (2022) -
The G Protein-Coupled Receptor UT of the Neuropeptide Urotensin II Displays Structural and Functional Chemokine Features
por: Castel, Hélène, et al.
Publicado: (2017) -
Down-Regulation of GABA(A) Receptor via Promiscuity with the Vasoactive Peptide Urotensin II Receptor. Potential Involvement in Astrocyte Plasticity
por: Desrues, Laurence, et al.
Publicado: (2012) -
A closer look at the role of urotensin II in the metabolic syndrome
por: Barrette, Pierre-Olivier, et al.
Publicado: (2012)