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Ubiquitin–proteasome system and the role of its inhibitors in cancer therapy

Despite all the other cells that have the potential to prevent cancer development and metastasis through tumour suppressor proteins, cancer cells can upregulate the ubiquitin–proteasome system (UPS) by which they can degrade tumour suppressor proteins and avoid apoptosis. This system plays an extens...

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Detalles Bibliográficos
Autores principales:	Aliabadi, Fatemeh, Sohrabi, Beheshteh, Mostafavi, Ebrahim, Pazoki-Toroudi, Hamidreza, Webster, Thomas J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8080017/ https://www.ncbi.nlm.nih.gov/pubmed/33906413 http://dx.doi.org/10.1098/rsob.200390

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