Cargando…

APE1 and SSRP1 is overexpressed in muscle invasive bladder cancer and associated with poor survival

BACKGROUND: Human apurinic/apyrimidinic (AP) endonuclease 1 (APE1) plays a critical role in DNA base excision repair (BER) pathway and has been reported to be overexpressed in multiple cancers. Previously, we have shown that histone chaperone FACT complex (Facilitates Chromatin Transcription, a hete...

Descripción completa

Detalles Bibliográficos
Autores principales:	Song, Heyu, Zeng, Jiping, Lele, Subodh, LaGrange, Chad A., Bhakat, Kishor K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8080038/ https://www.ncbi.nlm.nih.gov/pubmed/33948507 http://dx.doi.org/10.1016/j.heliyon.2021.e06756

Ejemplares similares

Elevated level of acetylation of APE1 in tumor cells modulates DNA damage repair
por: Sengupta, Shiladitya, et al.
Publicado: (2016)

Dual Regulatory Roles of Human AP-Endonuclease (APE1/Ref-1) in CDKN1A/p21 Expression
por: Sengupta, Shiladitya, et al.
Publicado: (2013)

The human AP-endonuclease 1 (APE1) is a DNA G-quadruplex structure binding protein and regulates KRAS expression in pancreatic ductal adenocarcinoma cells
por: Pramanik, Suravi, et al.
Publicado: (2022)

Human Apurinic/Apyrimidinic Endonuclease (APE1) Is Acetylated at DNA Damage Sites in Chromatin, and Acetylation Modulates Its DNA Repair Activity
por: Roychoudhury, Shrabasti, et al.
Publicado: (2017)

The Current Status of SSRP1 in Cancer: Tribulation and Road Ahead
por: Jia, Shengnan, et al.
Publicado: (2022)

Retracted: The Current Status of SSRP1 in Cancer: Tribulation and Road Ahead
por: Healthcare Engineering, Journal of
Publicado: (2023)

Lymphoepithelioma-like, a variant of urothelial carcinoma of the urinary bladder: a case report and systematic review for optimal treatment modality for disease-free survival
por: Yang, Andy W., et al.
Publicado: (2017)

Regulation of the human AP-endonuclease (APE1/Ref-1) expression by the tumor suppressor p53 in response to DNA damage
por: Zaky, Amira, et al.
Publicado: (2008)

Human AP-endonuclease (APE1/Ref-1) and its acetylation regulate YB-1/p300 recruitment and RNA polymerase II loading in the drug induced activation of multidrug resistance gene MDR1
por: Sengupta, Shiladitya, et al.
Publicado: (2010)

Carcinosarcoma of the Tunica Vaginalis Following Radiation Therapy for Localized Prostate Cancer
por: Viers, Charles D., et al.
Publicado: (2017)

Structure-specific recognition protein-1 (SSRP1) is an elongated homodimer that binds histones
por: Marcianò, Gabriele, et al.
Publicado: (2018)

Structural insights into multifunctionality of human FACT complex subunit hSSRP1
por: Li, Xuehui, et al.
Publicado: (2021)

Crystal Structure of Human SSRP1 Middle Domain Reveals a Role in DNA Binding
por: Zhang, Wenjuan, et al.
Publicado: (2015)

APE1 overexpression is associated with poor survival in patients with solid tumors: a meta-analysis
por: Yuan, Chun-Ling, et al.
Publicado: (2017)

SSRP1 Contributes to the Malignancy of Hepatocellular Carcinoma and Is Negatively Regulated by miR-497
por: Ding, Qianshan, et al.
Publicado: (2016)

SSRP1 influences colorectal cancer cell growth and apoptosis via the AKT pathway
por: Wang, Qian, et al.
Publicado: (2019)

SSRP1 affects the growth and apoptosis of gastric cancer cells through AKT pathway
por: Jin, Guohua, et al.
Publicado: (2022)

Endogenous oxidized DNA bases and APE1 regulate the formation of G-quadruplex structures in the genome
por: Roychoudhury, Shrabasti, et al.
Publicado: (2020)

SSRP1-mediated histone H1 eviction promotes replication origin assembly and accelerated development
por: Falbo, Lucia, et al.
Publicado: (2020)

Clinically Undiagnosed Prostate Carcinoma Metastatic to Renal Oncocytoma
por: Horn, Adam J., et al.
Publicado: (2012)

Regulation of limited N-terminal proteolysis of APE1 in tumor via acetylation and its role in cell proliferation
por: Bhakat, Kishor K., et al.
Publicado: (2016)

SSRP1 silencing inhibits the proliferation and malignancy of human glioma cells via the MAPK signaling pathway
por: Liao, Jianming, et al.
Publicado: (2017)

SSRP1 promotes colorectal cancer progression and is negatively regulated by miR‐28‐5p
por: Wu, Wei, et al.
Publicado: (2019)

SSRP1 Is a Prognostic Biomarker Correlated with CD8(+) T Cell Infiltration in Hepatocellular Carcinoma (HCC)
por: Luo, Guanshui, et al.
Publicado: (2021)

Mir204 and Mir211 suppress synovial inflammation and proliferation in rheumatoid arthritis by targeting Ssrp1
por: Wang, Qi-Shan, et al.
Publicado: (2022)

Nucleolar accumulation of APE1 depends on charged lysine residues that undergo acetylation upon genotoxic stress and modulate its BER activity in cells
por: Lirussi, Lisa, et al.
Publicado: (2012)

Urinary APE1/Ref-1: A Potential Bladder Cancer Biomarker
por: Choi, Sunga, et al.
Publicado: (2016)

APE1/Ref-1 as a Serological Biomarker for the Detection of Bladder Cancer
por: Shin, Ju Hyun, et al.
Publicado: (2015)

DLG1-AS1 is activated by MYC and drives the proliferation and migration of hepatocellular carcinoma cells through miR-497-5p/SSRP1 axis
por: Min, Jie, et al.
Publicado: (2021)

Upregulation of PD-L1 and APE1 is associated with tumorigenesis and poor prognosis of gastric cancer
por: Qing, Yi, et al.
Publicado: (2015)

Clinical Features of Sarcomatoid Carcinoma (Carcinosarcoma) of the Urinary Bladder: Analysis of 221 Cases
por: Wang, Jue, et al.
Publicado: (2010)

Nuclear Factor-κB Overexpression is Correlated with Poor Outcomes after Multimodality Bladder-Preserving Therapy in Patients with Muscle-Invasive Bladder Cancer
por: Chiang, Yun, et al.
Publicado: (2019)

Overexpression of YAP 1 contributes to progressive features and poor prognosis of human urothelial carcinoma of the bladder
por: Liu, Jian-Ye, et al.
Publicado: (2013)

Impact of reduced levels of APE1 transcripts on the survival of patients with urothelial carcinoma of the bladder
por: CHANTRE-JUSTINO, MARIANA, et al.
Publicado: (2015)

Quality and Safety of Minimally Invasive Surgery: Past, Present, and Future
por: McCrory, Bernadette, et al.
Publicado: (2014)

Derlin-1 overexpression confers poor prognosis in muscle invasive bladder cancer and contributes to chemoresistance and invasion through PI3K/AKT and ERK/MMP signaling
por: Dong, Qianze, et al.
Publicado: (2017)

From APE to APE-100: present and future of the APE project
por: Bacilieri, P, et al.
Publicado: (1988)

Correlation of APE1 with VEGFA and CD163(+) macrophage infiltration in bladder cancer and their prognostic significance
por: Wang, Lin-Ang, et al.
Publicado: (2020)

Uncovering the fine print of the CreER(T2)-LoxP system while generating a conditional knockout mouse model of Ssrp1 gene
por: Sandlesh, Poorva, et al.
Publicado: (2018)

APE1- and APE2-dependent DNA breaks in immunoglobulin class switch recombination
por: Guikema, Jeroen E.J., et al.
Publicado: (2007)

Cannot write session to /tmp/vufind_sessions/sess_jhkklubrv8m33bip0jve1ll8lb