Metformin pretreatment rescues olfactory memory associated with subependymal zone neurogenesis in a juvenile model of cranial irradiation

Cranial irradiation (IR) is an effective adjuvant therapy in the treatment of childhood brain tumors but results in long-lasting cognitive deficits associated with impaired neurogenesis, as evidenced in rodent models. Metformin has been shown to expand the endogenous neural stem cell (NSC) pool and...

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Detalles Bibliográficos
Autores principales: Derkach, Daniel, Kehtari, Tarlan, Renaud, Matthew, Heidari, Mohsen, Lakshman, Nishanth, Morshead, Cindi M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8080112/
https://www.ncbi.nlm.nih.gov/pubmed/33948569
http://dx.doi.org/10.1016/j.xcrm.2021.100231

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8080112/
https://www.ncbi.nlm.nih.gov/pubmed/33948569
http://dx.doi.org/10.1016/j.xcrm.2021.100231

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