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Functional and molecular effects of TNF-α on human iPSC-derived cardiomyocytes

Proinflammatory molecule tumor necrosis factor alpha (TNF-α) is predominantly elevated in cytokine storm as well as worsening cardiac function. Here we model the molecular and functional effects of TNF-α in cardiomyocytes (CMs) derived from human induced pluripotent stem cells (hiPSC). We found that...

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Detalles Bibliográficos
Autores principales:	Saraf, Anita, Rampoldi, Antonio, Chao, Myra, Li, Dong, Armand, Lawrence, Hwang, Hyun, Liu, Rui, Jha, Rajnesh, Fu, Haian, Maxwell, Joshua T., Xu, Chunhui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8080119/ https://www.ncbi.nlm.nih.gov/pubmed/33592567 http://dx.doi.org/10.1016/j.scr.2021.102218

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