A highly multiplexed droplet digital PCR assay to measure the intact HIV-1 proviral reservoir

Quantifying the replication-competent HIV reservoir is essential for evaluating curative strategies. Viral outgrowth assays (VOAs) underestimate the reservoir because they fail to induce all replication-competent proviruses. Single- or double-region HIV DNA assays overestimate it because they fail t...

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Detalles Bibliográficos
Autores principales: Levy, Claire N., Hughes, Sean M., Roychoudhury, Pavitra, Reeves, Daniel B., Amstuz, Chelsea, Zhu, Haiying, Huang, Meei-Li, Wei, Yulun, Bull, Marta E., Cassidy, Noah A.J., McClure, Jan, Frenkel, Lisa M., Stone, Mars, Bakkour, Sonia, Wonderlich, Elizabeth R., Busch, Michael P., Deeks, Steven G., Schiffer, Joshua T., Coombs, Robert W., Lehman, Dara A., Jerome, Keith R., Hladik, Florian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8080125/
https://www.ncbi.nlm.nih.gov/pubmed/33948574
http://dx.doi.org/10.1016/j.xcrm.2021.100243

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8080125/
https://www.ncbi.nlm.nih.gov/pubmed/33948574
http://dx.doi.org/10.1016/j.xcrm.2021.100243

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