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ABCB1 inhibition provides a novel therapeutic target to block TWIST1-induced migration in medulloblastoma

BACKGROUND: Therapeutic intervention in metastatic medulloblastoma is dependent on elucidating the underlying metastatic mechanism. We investigated whether an epithelial–mesenchymal transition (EMT)-like pathway could drive medulloblastoma metastasis. METHODS: A 3D Basement Membrane Extract (3D-BME)...

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Detalles Bibliográficos
Autores principales:	Nasir, Aishah, Cardall, Alice, Othman, Ramadhan T, Nicolaou, Niovi, Lourdusamy, Anbarasu, Linke, Franziska, Onion, David, Ryzhova, Marina, Cameron, Hanna, Valente, Cara, Ritchie, Alison, Korshunov, Andrey, Pfister, Stefan M, Grabowska, Anna M, Kerr, Ian D, Coyle, Beth
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2021
Materias:	Basic and Translational Investigations
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8080134/ https://www.ncbi.nlm.nih.gov/pubmed/33948561 http://dx.doi.org/10.1093/noajnl/vdab030

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