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Risk factors for Toxoplasma gondii seropositivity in the Old Order Amish
Toxoplasma gondii (T. gondii) is an important human disease-causing parasite. In the USA, T. gondii infects >10% of the population, accrues economic losses of US$3.6 billion/year, and ranks as the second leading culprit of foodborne illness-related fatalities. We assessed toxoplasmosis risk among...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cambridge University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8080217/ https://www.ncbi.nlm.nih.gov/pubmed/33234182 http://dx.doi.org/10.1017/S0950268820002897 |
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author | Markon, A. O. Ryan, K. A. Wadhawan, A. Pavlovich, M. Groer, M. W. Punzalan, C. Gensheimer, K. Jones, J. L. Daue, M. L. Dagdag, A. Donnelly, P. Peng, X. Pollin, T. I. Mitchell, B. D. Postolache, T. T. |
author_facet | Markon, A. O. Ryan, K. A. Wadhawan, A. Pavlovich, M. Groer, M. W. Punzalan, C. Gensheimer, K. Jones, J. L. Daue, M. L. Dagdag, A. Donnelly, P. Peng, X. Pollin, T. I. Mitchell, B. D. Postolache, T. T. |
author_sort | Markon, A. O. |
collection | PubMed |
description | Toxoplasma gondii (T. gondii) is an important human disease-causing parasite. In the USA, T. gondii infects >10% of the population, accrues economic losses of US$3.6 billion/year, and ranks as the second leading culprit of foodborne illness-related fatalities. We assessed toxoplasmosis risk among the Old Order Amish, a mostly homogenous population with a high prevalence of T. gondii seropositivity, using a questionnaire focusing on food consumption/preparation behaviours and environmental risk factors. Analyses were conducted using multiple logistic regression. Consuming raw meat, rare meat, or unpasteurised cow or goat milk products was associated with increased odds of seropositivity (unadjusted Odds Ratios: 2.192, 1.613, and 1.718 , respectively). In separate models by sex, consuming raw meat, or consuming unpasteurised cow or goat milk products, was associated with increased odds of seropositivity among women; washing hands after touching meat with decreased odds of seropositivity among women (adjusted OR (AOR): 0.462); and cleaning cat litterbox with increased odds of seropositivity among men (AOR: 5.241). This is the first study to assess associations between behavioural and environmental risk factors and T. gondii seropositivity in a US population with high seroprevalence for T. gondii. Our study emphasises the importance of proper food safety behaviours to avoid the risk of infection. |
format | Online Article Text |
id | pubmed-8080217 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Cambridge University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-80802172021-05-13 Risk factors for Toxoplasma gondii seropositivity in the Old Order Amish Markon, A. O. Ryan, K. A. Wadhawan, A. Pavlovich, M. Groer, M. W. Punzalan, C. Gensheimer, K. Jones, J. L. Daue, M. L. Dagdag, A. Donnelly, P. Peng, X. Pollin, T. I. Mitchell, B. D. Postolache, T. T. Epidemiol Infect Original Paper Toxoplasma gondii (T. gondii) is an important human disease-causing parasite. In the USA, T. gondii infects >10% of the population, accrues economic losses of US$3.6 billion/year, and ranks as the second leading culprit of foodborne illness-related fatalities. We assessed toxoplasmosis risk among the Old Order Amish, a mostly homogenous population with a high prevalence of T. gondii seropositivity, using a questionnaire focusing on food consumption/preparation behaviours and environmental risk factors. Analyses were conducted using multiple logistic regression. Consuming raw meat, rare meat, or unpasteurised cow or goat milk products was associated with increased odds of seropositivity (unadjusted Odds Ratios: 2.192, 1.613, and 1.718 , respectively). In separate models by sex, consuming raw meat, or consuming unpasteurised cow or goat milk products, was associated with increased odds of seropositivity among women; washing hands after touching meat with decreased odds of seropositivity among women (adjusted OR (AOR): 0.462); and cleaning cat litterbox with increased odds of seropositivity among men (AOR: 5.241). This is the first study to assess associations between behavioural and environmental risk factors and T. gondii seropositivity in a US population with high seroprevalence for T. gondii. Our study emphasises the importance of proper food safety behaviours to avoid the risk of infection. Cambridge University Press 2020-11-25 /pmc/articles/PMC8080217/ /pubmed/33234182 http://dx.doi.org/10.1017/S0950268820002897 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Paper Markon, A. O. Ryan, K. A. Wadhawan, A. Pavlovich, M. Groer, M. W. Punzalan, C. Gensheimer, K. Jones, J. L. Daue, M. L. Dagdag, A. Donnelly, P. Peng, X. Pollin, T. I. Mitchell, B. D. Postolache, T. T. Risk factors for Toxoplasma gondii seropositivity in the Old Order Amish |
title | Risk factors for Toxoplasma gondii seropositivity in the Old Order Amish |
title_full | Risk factors for Toxoplasma gondii seropositivity in the Old Order Amish |
title_fullStr | Risk factors for Toxoplasma gondii seropositivity in the Old Order Amish |
title_full_unstemmed | Risk factors for Toxoplasma gondii seropositivity in the Old Order Amish |
title_short | Risk factors for Toxoplasma gondii seropositivity in the Old Order Amish |
title_sort | risk factors for toxoplasma gondii seropositivity in the old order amish |
topic | Original Paper |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8080217/ https://www.ncbi.nlm.nih.gov/pubmed/33234182 http://dx.doi.org/10.1017/S0950268820002897 |
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