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Co-dominant neutralizing epitopes make anti-measles immunity resistant to viral evolution

Munoz-Alia and colleagues(1) demonstrate that neutralizing antibody immunity to measles resists viral evolutionary escape because it targets numerous distinct viral epitopes. Their work contributes to our understanding of what determines whether a virus can evolve to evade immunity.

Detalles Bibliográficos
Autores principales: Greaney, Allison J., Welsh, Frances C., Bloom, Jesse D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8080248/
https://www.ncbi.nlm.nih.gov/pubmed/33948584
http://dx.doi.org/10.1016/j.xcrm.2021.100257
Descripción
Sumario:Munoz-Alia and colleagues(1) demonstrate that neutralizing antibody immunity to measles resists viral evolutionary escape because it targets numerous distinct viral epitopes. Their work contributes to our understanding of what determines whether a virus can evolve to evade immunity.