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Co-dominant neutralizing epitopes make anti-measles immunity resistant to viral evolution

Munoz-Alia and colleagues(1) demonstrate that neutralizing antibody immunity to measles resists viral evolutionary escape because it targets numerous distinct viral epitopes. Their work contributes to our understanding of what determines whether a virus can evolve to evade immunity.

Detalles Bibliográficos
Autores principales: Greaney, Allison J., Welsh, Frances C., Bloom, Jesse D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8080248/
https://www.ncbi.nlm.nih.gov/pubmed/33948584
http://dx.doi.org/10.1016/j.xcrm.2021.100257
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author Greaney, Allison J.
Welsh, Frances C.
Bloom, Jesse D.
author_facet Greaney, Allison J.
Welsh, Frances C.
Bloom, Jesse D.
author_sort Greaney, Allison J.
collection PubMed
description Munoz-Alia and colleagues(1) demonstrate that neutralizing antibody immunity to measles resists viral evolutionary escape because it targets numerous distinct viral epitopes. Their work contributes to our understanding of what determines whether a virus can evolve to evade immunity.
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spelling pubmed-80802482021-05-03 Co-dominant neutralizing epitopes make anti-measles immunity resistant to viral evolution Greaney, Allison J. Welsh, Frances C. Bloom, Jesse D. Cell Rep Med Preview Munoz-Alia and colleagues(1) demonstrate that neutralizing antibody immunity to measles resists viral evolutionary escape because it targets numerous distinct viral epitopes. Their work contributes to our understanding of what determines whether a virus can evolve to evade immunity. Elsevier 2021-04-20 /pmc/articles/PMC8080248/ /pubmed/33948584 http://dx.doi.org/10.1016/j.xcrm.2021.100257 Text en © 2021 The Author(s) https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Preview
Greaney, Allison J.
Welsh, Frances C.
Bloom, Jesse D.
Co-dominant neutralizing epitopes make anti-measles immunity resistant to viral evolution
title Co-dominant neutralizing epitopes make anti-measles immunity resistant to viral evolution
title_full Co-dominant neutralizing epitopes make anti-measles immunity resistant to viral evolution
title_fullStr Co-dominant neutralizing epitopes make anti-measles immunity resistant to viral evolution
title_full_unstemmed Co-dominant neutralizing epitopes make anti-measles immunity resistant to viral evolution
title_short Co-dominant neutralizing epitopes make anti-measles immunity resistant to viral evolution
title_sort co-dominant neutralizing epitopes make anti-measles immunity resistant to viral evolution
topic Preview
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8080248/
https://www.ncbi.nlm.nih.gov/pubmed/33948584
http://dx.doi.org/10.1016/j.xcrm.2021.100257
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