Cargando…

Experimental observation of the sequence of tibial plateau chondrocyte and matrix degeneration in spontaneous osteoarthritis in Guinea pigs

BACKGROUND: To observe the sequence of chondrocyte degeneration and matrix degradation in the superficial surface cartilage of the tibial plateau in guinea pigs with spontaneous knee osteoarthritis (OA). METHODS: Sixty guinea pigs were euthanized at the ages of 8 months (n = 20),10 months (n = 20) a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Xiao-jian, Wei, Lei, Xue, Yan, Li, Rong-shan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8080336/ https://www.ncbi.nlm.nih.gov/pubmed/33910538 http://dx.doi.org/10.1186/s12891-021-04281-x

Ejemplares similares

Increased Chondrocyte Apoptosis Is Associated with Progression of Osteoarthritis in Spontaneous Guinea Pig Models of the Disease
por: Zamli, Zaitunnatakhin, et al.
Publicado: (2013)

Differential proteomic analysis of tibial subchondral bone from male and female guinea pigs with spontaneous osteoarthritis
por: Wang, Ying, et al.
Publicado: (2021)

Dihydrotanshinone I protects human chondrocytes and alleviates damage from spontaneous osteoarthritis in a guinea pig model
por: Zhang, Yan-Zhuo, et al.
Publicado: (2023)

Intra-Articular Injection of (−)-Epigallocatechin 3-Gallate (EGCG) Ameliorates Cartilage Degeneration in Guinea Pigs with Spontaneous Osteoarthritis
por: Huang, Hsuan-Ti, et al.
Publicado: (2021)

Defining matrix Gla protein expression in the Dunkin-Hartley guinea pig model of spontaneous osteoarthritis
por: Ma, Xun, et al.
Publicado: (2021)

The Osteoarthritis Natural Progress and Changes in Intraosseous Pressure of the Guinea Pig Model in Different Degeneration Stages
por: Wang, Shuo, et al.
Publicado: (2022)

Diagnostic issue on spontaneous osteonecrosis of medial tibial plateau
por: Jiang, Jun, et al.
Publicado: (2019)

Arthroscopic Autologous Chondrocyte Bone Grafting of a Lateral Tibial Plateau Chondral Defect
por: DeFroda, Steven F., et al.
Publicado: (2021)

Spontaneous Tumourigenesis in Aged Guinea-pigs
por: Lipschutz, A., et al.
Publicado: (1959)

GIT1 gene deletion delays chondrocyte differentiation and healing of tibial plateau fracture through suppressing proliferation and apoptosis of chondrocyte
por: Chen, Peng, et al.
Publicado: (2017)

Direct transplantation of mesenchymal stem cells into the knee joints of Hartley strain guinea pigs with spontaneous osteoarthritis
por: Sato, Mitsuhiko, et al.
Publicado: (2012)

Morphological and mechanical alterations in articular cartilage and subchondral bone during spontaneous hip osteoarthritis in guinea pigs
por: Gao, Jiazi, et al.
Publicado: (2023)

TIBIAL PLATEAU FRACTURES
por: Júnior, Mauricio Kfuri, et al.
Publicado: (2015)

Osteoarthritis: degeneration of matrix or cells?
por: Aigner, T
Publicado: (2004)

HUMAN GUINEA-PIGS EXPERIMENTATION IN MAN
Publicado: (1967)

Human Guinea Pigs Experimentation on Man
por: Merskey, H.
Publicado: (1967)

Isorhynchophylline alleviates cartilage degeneration in osteoarthritis by activating autophagy of chondrocytes
por: Jiang, Jieyun, et al.
Publicado: (2023)

Calcitonin attenuates cartilage degeneration and nociception in an experimental rat model of osteoarthritis: role of TGF-β in chondrocytes
por: Wen, Zhi-Hong, et al.
Publicado: (2016)

Spontaneous Ameloblastic Fibroma in a Young Guinea Pig
por: Tanaka, Makoto, et al.
Publicado: (2013)

Open-wedge high tibial osteotomy for spontaneous osteonecrosis of the medial tibial plateau shows excellent clinical outcomes
por: Goshima, Kenichi, et al.
Publicado: (2020)

Clinical Characteristics and Treatment of Spontaneous Osteonecrosis of Medial Tibial Plateau: A Retrospective Case Study
por: Yang, Wei-Ming, et al.
Publicado: (2018)

Association of osteoporosis and varus inclination of the tibial plateau in postmenopausal women with advanced osteoarthritis of the knee
por: Wang, Shun-Ping, et al.
Publicado: (2021)

Statin prevents chondrocyte aging and degeneration of articular cartilage in osteoarthritis (OA)
por: Yudoh, Kazuo, et al.
Publicado: (2010)

Pink1-Mediated Chondrocytic Mitophagy Contributes to Cartilage Degeneration in Osteoarthritis
por: Shin, Hyo Jung, et al.
Publicado: (2019)

THE EXPERIMENTAL PRODUCTION OF NECROSIS OF THE LIVER IN THE GUINEA PIG
por: Fleisher, Moyer S., et al.
Publicado: (1914)

Low‐intensity pulsed ultrasound inhibits VEGFA expression in chondrocytes and protects against cartilage degeneration in experimental osteoarthritis
por: Guan, Mengtong, et al.
Publicado: (2020)

EXPERIMENTAL PNEUMONIA IN GUINEA PIGS : II. EFFECT OF ANTI-AUTOLYSATE SERA ON PNEUMOCOCCUS PNEUMONIA IN GUINEA PIGS
por: Parker, Julia T.
Publicado: (1929)

Spontaneous Healing of Mycobacterium ulcerans Lesions in the Guinea Pig Model
por: Silva-Gomes, Rita, et al.
Publicado: (2015)

Spontaneously Myopic Guinea Pig: Model of Early Pathologic Myopia
por: Zhang, Yue, et al.
Publicado: (2023)

Protective role of Achyranthes bidentata polysaccharides against chondrocyte extracellular matrix degeneration through lncRNA GAS5 in osteoarthritis
por: Fu, Changlong, et al.
Publicado: (2022)

EXPERIMENTAL STUDY OF DIPHTHERITIC POLYNEURITIS IN THE RABBIT AND GUINEA PIG : I. IMMUNOLOGIC AND HISTOPATHOLOGIC OBSERVATIONS
por: Waksman, Byron H., et al.
Publicado: (1957)

Tibial plateau fractures: Fracture patterns and computed tomography evaluation of tibial plateau fractures in winter sports
por: Gebel, Philipp Jan, et al.
Publicado: (2018)

Calorie restriction with regular chow, but not a high-fat diet, delays onset of spontaneous osteoarthritis in the Hartley guinea pig model
por: Radakovich, Lauren B., et al.
Publicado: (2019)

Tibial Plateau Fractures in Elderly Patients
por: Rozell, Joshua C., et al.
Publicado: (2016)

Arthroscopic Management for Tibial Plateau Fractures
Publicado: (1991)

Why tibial plateau fractures are overlooked
por: Kiel, Cecilie Mullerup, et al.
Publicado: (2018)

Epidemiological characterization of tibial plateau fractures
por: Reátiga Aguilar, Juan, et al.
Publicado: (2022)

Beclin 1 overexpression inhibits chondrocyte apoptosis and downregulates extracellular matrix metabolism in osteoarthritis
por: Song, Bin, et al.
Publicado: (2017)

Comparison of extended anterolateral approach in treatment of simple/complex tibial plateau fracture with posterolateral tibial plateau fracture
por: Jiang, Liangjun, et al.
Publicado: (2018)

An analysis on the effect of the three-incision combined approach for complex fracture of tibial plateau involving the posterolateral tibial plateau
por: Hong, Guqi, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_1h3trtssfkovrief47ura86mtl