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Modified endoscopic transnasal orbital apex decompression in dysthyroid optic neuropathy

BACKGROUND: To describe the surgical technique and assess the clinical efficacy and safety of modified endoscopic transnasal orbital apex decompression in the treatment of dysthyroid optic neuropathy. METHODS: In this retrospective research, forty-two subjects (74 orbits) who underwent modified endo...

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Autores principales: Tu, Yunhai, Xu, Mingna, Kim, Andy D., Wang, Michael T. M., Pan, Zhaoqi, Wu, Wencan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8080388/
https://www.ncbi.nlm.nih.gov/pubmed/33910645
http://dx.doi.org/10.1186/s40662-021-00238-2
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author Tu, Yunhai
Xu, Mingna
Kim, Andy D.
Wang, Michael T. M.
Pan, Zhaoqi
Wu, Wencan
author_facet Tu, Yunhai
Xu, Mingna
Kim, Andy D.
Wang, Michael T. M.
Pan, Zhaoqi
Wu, Wencan
author_sort Tu, Yunhai
collection PubMed
description BACKGROUND: To describe the surgical technique and assess the clinical efficacy and safety of modified endoscopic transnasal orbital apex decompression in the treatment of dysthyroid optic neuropathy. METHODS: In this retrospective research, forty-two subjects (74 orbits) who underwent modified endoscopic transnasal orbital apex decompression for the treatment of dysthyroid optic neuropathy were enrolled. Preoperative and postoperative best-corrected visual acuity (BCVA), visual field mean deviation (MD), Hertel exophthalmometry, and new onset diplopia were assessed before and after the intervention. The Wilcoxon test was used for differential analysis. Linear mixed-models’ analyses were conducted to assess the potential predictors for BCVA change. RESULTS: Postoperatively, the mean BCVA improved from 0.70 ± 0.62 logMAR to 0.22 ± 0.33 logMAR. BCVA significantly improved in 69 eyes (93%), remained stable in 4 eyes (5%) and deteriorated in 1 eye (1%). MD of visual fields improved from −13.73 ± 9.22 dB to −7.23 ± 7.04 dB. Proptosis decreased from 19.57 ± 3.38 mm to 16.35 ± 3.01 mm. Preoperative BCVA, MD of visual fields and medical rectus diameter were independent factors associated with improvements in BCVA (P < 0.05) by linear mixed-models’ analyses. Eighteen patients (42.9%) developed new diplopia postoperatively. CONCLUSION: Modified endoscopic transnasal orbital apex decompression effectively restores vision in dysthyroid optic neuropathy. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s40662-021-00238-2.
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spelling pubmed-80803882021-04-29 Modified endoscopic transnasal orbital apex decompression in dysthyroid optic neuropathy Tu, Yunhai Xu, Mingna Kim, Andy D. Wang, Michael T. M. Pan, Zhaoqi Wu, Wencan Eye Vis (Lond) Research BACKGROUND: To describe the surgical technique and assess the clinical efficacy and safety of modified endoscopic transnasal orbital apex decompression in the treatment of dysthyroid optic neuropathy. METHODS: In this retrospective research, forty-two subjects (74 orbits) who underwent modified endoscopic transnasal orbital apex decompression for the treatment of dysthyroid optic neuropathy were enrolled. Preoperative and postoperative best-corrected visual acuity (BCVA), visual field mean deviation (MD), Hertel exophthalmometry, and new onset diplopia were assessed before and after the intervention. The Wilcoxon test was used for differential analysis. Linear mixed-models’ analyses were conducted to assess the potential predictors for BCVA change. RESULTS: Postoperatively, the mean BCVA improved from 0.70 ± 0.62 logMAR to 0.22 ± 0.33 logMAR. BCVA significantly improved in 69 eyes (93%), remained stable in 4 eyes (5%) and deteriorated in 1 eye (1%). MD of visual fields improved from −13.73 ± 9.22 dB to −7.23 ± 7.04 dB. Proptosis decreased from 19.57 ± 3.38 mm to 16.35 ± 3.01 mm. Preoperative BCVA, MD of visual fields and medical rectus diameter were independent factors associated with improvements in BCVA (P < 0.05) by linear mixed-models’ analyses. Eighteen patients (42.9%) developed new diplopia postoperatively. CONCLUSION: Modified endoscopic transnasal orbital apex decompression effectively restores vision in dysthyroid optic neuropathy. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s40662-021-00238-2. BioMed Central 2021-04-28 /pmc/articles/PMC8080388/ /pubmed/33910645 http://dx.doi.org/10.1186/s40662-021-00238-2 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Tu, Yunhai
Xu, Mingna
Kim, Andy D.
Wang, Michael T. M.
Pan, Zhaoqi
Wu, Wencan
Modified endoscopic transnasal orbital apex decompression in dysthyroid optic neuropathy
title Modified endoscopic transnasal orbital apex decompression in dysthyroid optic neuropathy
title_full Modified endoscopic transnasal orbital apex decompression in dysthyroid optic neuropathy
title_fullStr Modified endoscopic transnasal orbital apex decompression in dysthyroid optic neuropathy
title_full_unstemmed Modified endoscopic transnasal orbital apex decompression in dysthyroid optic neuropathy
title_short Modified endoscopic transnasal orbital apex decompression in dysthyroid optic neuropathy
title_sort modified endoscopic transnasal orbital apex decompression in dysthyroid optic neuropathy
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8080388/
https://www.ncbi.nlm.nih.gov/pubmed/33910645
http://dx.doi.org/10.1186/s40662-021-00238-2
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