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DNA end resection and its role in DNA replication and DSB repair choice in mammalian cells

DNA end resection has a key role in double-strand break repair and DNA replication. Defective DNA end resection can cause malfunctions in DNA repair and replication, leading to greater genomic instability. DNA end resection is initiated by MRN-CtIP generating short, 3′-single-stranded DNA (ssDNA). T...

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Detalles Bibliográficos
Autores principales:	Zhao, Fei, Kim, Wootae, Kloeber, Jake A., Lou, Zhenkun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8080561/ https://www.ncbi.nlm.nih.gov/pubmed/33122806 http://dx.doi.org/10.1038/s12276-020-00519-1

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