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Transcriptional regulatory network for the establishment of CD8(+) T cell exhaustion
Chronic infection with persistent antigenic stimulation results in the generation of exhausted CD8(+) T cells, which are considered defective effector CD8(+) T cells, and thus compromises effective immune responses. However, recent studies have illustrated that exhausted CD8(+) T cells may be purpos...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8080584/ https://www.ncbi.nlm.nih.gov/pubmed/33627794 http://dx.doi.org/10.1038/s12276-021-00568-0 |