Cargando…
Shaping of the 3D genome by the ATPase machine cohesin
The spatial organization of the genome is critical for fundamental biological processes, including transcription, genome replication, and segregation. Chromatin is compacted and organized with defined patterns and proper dynamics during the cell cycle. Aided by direct visualization and indirect geno...
Autores principales: | Kim, Yoori, Yu, Hongtao |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8080590/ https://www.ncbi.nlm.nih.gov/pubmed/33268833 http://dx.doi.org/10.1038/s12276-020-00526-2 |
Ejemplares similares
-
Cohesin’s ATPase Activity Couples Cohesin Loading onto DNA with Smc3 Acetylation
por: Ladurner, Rene, et al.
Publicado: (2014) -
The ATPases of cohesin interface with regulators to modulate cohesin-mediated DNA tethering
por: Çamdere, Gamze, et al.
Publicado: (2015) -
Cohesin-dependent globules and heterochromatin shape 3D genome architecture in S. pombe
por: Mizuguchi, Takeshi, et al.
Publicado: (2014) -
Cohesin Releases DNA through Asymmetric ATPase-Driven Ring Opening
por: Elbatsh, Ahmed M.O., et al.
Publicado: (2016) -
The structure of the cohesin ATPase elucidates the mechanism of SMC–kleisin ring opening
por: Muir, Kyle W., et al.
Publicado: (2020)