Cargando…

Dyslipidemia and its associated factors in southern Iranian women, Bandare-Kong Cohort study, a cross-sectional survey

Dyslipidemia, a major risk factor for cardiovascular diseases, has become a global issue. Due to the variations in the prevalence of dyslipidemia, this study aimed to evaluate dyslipidemia and its associated factors in women of the Bandare-Kong Cohort Study (BKNCD). This study was conducted on women...

Descripción completa

Detalles Bibliográficos
Autores principales: Nikparvar, Marzieh, Khaladeh, Mohadeseh, Yousefi, Hadi, Vahidi Farashah, Mohammadsadegh, Moayedi, Behzad, Kheirandish, Masoumeh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8080669/
https://www.ncbi.nlm.nih.gov/pubmed/33911149
http://dx.doi.org/10.1038/s41598-021-88680-z
_version_ 1783685482818830336
author Nikparvar, Marzieh
Khaladeh, Mohadeseh
Yousefi, Hadi
Vahidi Farashah, Mohammadsadegh
Moayedi, Behzad
Kheirandish, Masoumeh
author_facet Nikparvar, Marzieh
Khaladeh, Mohadeseh
Yousefi, Hadi
Vahidi Farashah, Mohammadsadegh
Moayedi, Behzad
Kheirandish, Masoumeh
author_sort Nikparvar, Marzieh
collection PubMed
description Dyslipidemia, a major risk factor for cardiovascular diseases, has become a global issue. Due to the variations in the prevalence of dyslipidemia, this study aimed to evaluate dyslipidemia and its associated factors in women of the Bandare-Kong Cohort Study (BKNCD). This study was conducted on women from the population-based BKNCD, as part of the Prospective Epidemiological Research Studies in IrAN (PERSIAN). Sociodemographic data, medical history, and anthropometric indices were collected. Dyslipidemia was defined as any lipid abnormality including low-density lipoprotein (LDL) ≥ 160, total cholesterol (TC) ≥ 240, high-density lipoprotein (HDL) < 40, or triglyceride > 200 mg/dl. From the 2223 women in this study (mean age: 48.28 ± 9.26 years), dyslipidemia was observed in 851 (38.3%). High TC was the most common lipid abnormality (18.5%) followed by high LDL (17.7%). Dyslipidemia was most prevalent among women aged 55–70 years, the married, those with < 6 years of education, the unemployed, the overweight or obese, with low socioeconomic status, diabetes, hypertension, and high waist circumference, those using the hookah and living in urban areas. Logistic regression revealed that women with high waist-to-hip ratio (WHR) (OR = 2.22, 95% CI 1.60–3.08), those aged 45–54 years (OR = 1.34, 95% CI 1.07–1.68) and 55–70 years (OR = 1.33, 95% CI 1.03–1.72), and those living in urban areas (OR = 1.35, 95% CI 1.05–1.73) were at significantly increased risk of dyslipidemia. In addition, the results were confirmed using deep neural network models. Dyslipidemia was highly prevalent in Iranian women in the southern coastal region. Central obesity, age over 45 years, and living in urban areas appear to be relatively significant risk factors for dyslipidemia among women.
format Online
Article
Text
id pubmed-8080669
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Nature Publishing Group UK
record_format MEDLINE/PubMed
spelling pubmed-80806692021-04-30 Dyslipidemia and its associated factors in southern Iranian women, Bandare-Kong Cohort study, a cross-sectional survey Nikparvar, Marzieh Khaladeh, Mohadeseh Yousefi, Hadi Vahidi Farashah, Mohammadsadegh Moayedi, Behzad Kheirandish, Masoumeh Sci Rep Article Dyslipidemia, a major risk factor for cardiovascular diseases, has become a global issue. Due to the variations in the prevalence of dyslipidemia, this study aimed to evaluate dyslipidemia and its associated factors in women of the Bandare-Kong Cohort Study (BKNCD). This study was conducted on women from the population-based BKNCD, as part of the Prospective Epidemiological Research Studies in IrAN (PERSIAN). Sociodemographic data, medical history, and anthropometric indices were collected. Dyslipidemia was defined as any lipid abnormality including low-density lipoprotein (LDL) ≥ 160, total cholesterol (TC) ≥ 240, high-density lipoprotein (HDL) < 40, or triglyceride > 200 mg/dl. From the 2223 women in this study (mean age: 48.28 ± 9.26 years), dyslipidemia was observed in 851 (38.3%). High TC was the most common lipid abnormality (18.5%) followed by high LDL (17.7%). Dyslipidemia was most prevalent among women aged 55–70 years, the married, those with < 6 years of education, the unemployed, the overweight or obese, with low socioeconomic status, diabetes, hypertension, and high waist circumference, those using the hookah and living in urban areas. Logistic regression revealed that women with high waist-to-hip ratio (WHR) (OR = 2.22, 95% CI 1.60–3.08), those aged 45–54 years (OR = 1.34, 95% CI 1.07–1.68) and 55–70 years (OR = 1.33, 95% CI 1.03–1.72), and those living in urban areas (OR = 1.35, 95% CI 1.05–1.73) were at significantly increased risk of dyslipidemia. In addition, the results were confirmed using deep neural network models. Dyslipidemia was highly prevalent in Iranian women in the southern coastal region. Central obesity, age over 45 years, and living in urban areas appear to be relatively significant risk factors for dyslipidemia among women. Nature Publishing Group UK 2021-04-28 /pmc/articles/PMC8080669/ /pubmed/33911149 http://dx.doi.org/10.1038/s41598-021-88680-z Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Nikparvar, Marzieh
Khaladeh, Mohadeseh
Yousefi, Hadi
Vahidi Farashah, Mohammadsadegh
Moayedi, Behzad
Kheirandish, Masoumeh
Dyslipidemia and its associated factors in southern Iranian women, Bandare-Kong Cohort study, a cross-sectional survey
title Dyslipidemia and its associated factors in southern Iranian women, Bandare-Kong Cohort study, a cross-sectional survey
title_full Dyslipidemia and its associated factors in southern Iranian women, Bandare-Kong Cohort study, a cross-sectional survey
title_fullStr Dyslipidemia and its associated factors in southern Iranian women, Bandare-Kong Cohort study, a cross-sectional survey
title_full_unstemmed Dyslipidemia and its associated factors in southern Iranian women, Bandare-Kong Cohort study, a cross-sectional survey
title_short Dyslipidemia and its associated factors in southern Iranian women, Bandare-Kong Cohort study, a cross-sectional survey
title_sort dyslipidemia and its associated factors in southern iranian women, bandare-kong cohort study, a cross-sectional survey
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8080669/
https://www.ncbi.nlm.nih.gov/pubmed/33911149
http://dx.doi.org/10.1038/s41598-021-88680-z
work_keys_str_mv AT nikparvarmarzieh dyslipidemiaanditsassociatedfactorsinsoutherniranianwomenbandarekongcohortstudyacrosssectionalsurvey
AT khaladehmohadeseh dyslipidemiaanditsassociatedfactorsinsoutherniranianwomenbandarekongcohortstudyacrosssectionalsurvey
AT yousefihadi dyslipidemiaanditsassociatedfactorsinsoutherniranianwomenbandarekongcohortstudyacrosssectionalsurvey
AT vahidifarashahmohammadsadegh dyslipidemiaanditsassociatedfactorsinsoutherniranianwomenbandarekongcohortstudyacrosssectionalsurvey
AT moayedibehzad dyslipidemiaanditsassociatedfactorsinsoutherniranianwomenbandarekongcohortstudyacrosssectionalsurvey
AT kheirandishmasoumeh dyslipidemiaanditsassociatedfactorsinsoutherniranianwomenbandarekongcohortstudyacrosssectionalsurvey