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Development of a miRNA-controlled dual-sensing system and its application for targeting miR-21 signaling in tumorigenesis

MicroRNAs (miRNAs) are considered to be strong prognostic markers and key therapeutic targets in human diseases, especially cancer. A sensitive monitoring platform for cancer-associated miRNA (oncomiR) action is needed for mechanistic studies, preclinical evaluation, and inhibitor screening. In this...

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Detalles Bibliográficos
Autores principales: Seo, Yoona, Kim, Sung Soo, Kim, Namdoo, Cho, Sungchan, Park, Jong Bae, Kim, Jong Heon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8080684/
https://www.ncbi.nlm.nih.gov/pubmed/33311703
http://dx.doi.org/10.1038/s12276-020-00537-z