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Evogliptin, a dipeptidyl peptidase-4 inhibitor, attenuates pathological retinal angiogenesis by suppressing vascular endothelial growth factor-induced Arf6 activation
Dipeptidyl peptidase-4 (DPP-4) inhibitors are used for the treatment of type 2 diabetes mellitus (DM). Recent studies have shown that beyond their effect in lowing glucose, DPP-4 inhibitors mitigate DM-related microvascular complications, such as diabetic retinopathy. However, the mechanism by which...
Autores principales: | Seo, Songyi, Kim, Mi-Kyung, Kim, Ryul-I, Yeo, Yeongju, Kim, Koung Li, Suh, Wonhee |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8080693/ https://www.ncbi.nlm.nih.gov/pubmed/33051573 http://dx.doi.org/10.1038/s12276-020-00512-8 |
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