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LGK974 suppresses lipopolysaccharide-induced endotoxemia in mice by modulating the crosstalk between the Wnt/β-catenin and NF-κB pathways

Endotoxemia, a type of sepsis caused by gram-negative bacterial endotoxin [i.e., lipopolysaccharide (LPS)], is associated with manifestations such as cytokine storm; failure of multiple organs, including the liver; and a high mortality rate. We investigated the effect and mechanism of action of LGK9...

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Detalles Bibliográficos
Autores principales:	Jang, Jaewoong, Song, Jaewon, Lee, Hyunji, Sim, Inae, Kwon, Young V., Jho, Eek-hoon, Yoon, Yoosik
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8080716/ https://www.ncbi.nlm.nih.gov/pubmed/33692475 http://dx.doi.org/10.1038/s12276-021-00577-z

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