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Splenectomy improves liver fibrosis via tumor necrosis factor superfamily 14 (LIGHT) through the JNK/TGF-β1 signaling pathway

Splenectomy has been reported to improve liver fibrosis in patients with cirrhosis and hypersplenism. However, the mechanisms remain unclear. Tumor necrosis factor superfamily 14 (TNFSF14; also known as LIGHT) is highly expressed in the context of fibrosis and promotes disease progression in patient...

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Detalles Bibliográficos
Autores principales:	Liang, Qing-shan, Xie, Jian-Gang, Yu, ChaoPing, Feng, ZhuSheng, Ma, JingChang, Zhang, Yuan, Wang, Dong, Lu, JianGuo, Zhuang, Ran, Yin, Jikai
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8080781/ https://www.ncbi.nlm.nih.gov/pubmed/33654222 http://dx.doi.org/10.1038/s12276-021-00574-2

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