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Pro-inflammatory interleukin-6 signaling links cognitive impairments and peripheral metabolic alterations in Alzheimer’s disease

Alzheimer’s disease (AD) is associated with memory impairment and altered peripheral metabolism. Mounting evidence indicates that abnormal signaling in a brain-periphery metabolic axis plays a role in AD pathophysiology. The activation of pro-inflammatory pathways in the brain, including the interle...

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Detalles Bibliográficos
Autores principales:	Lyra e Silva, Natalia M., Gonçalves, Rafaella A., Pascoal, Tharick A., Lima-Filho, Ricardo A. S., Resende, Elisa de Paula França, Vieira, Erica L. M., Teixeira, Antonio L., de Souza, Leonardo C., Peny, Julyanna A., Fortuna, Juliana T. S., Furigo, Isadora C., Hashiguchi, Debora, Miya-Coreixas, Vivian S., Clarke, Julia R., Abisambra, Jose F., Longo, Beatriz M., Donato, Jose, Fraser, Paul E., Rosa-Neto, Pedro, Caramelli, Paulo, Ferreira, Sergio T., De Felice, Fernanda G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8080782/ https://www.ncbi.nlm.nih.gov/pubmed/33911072 http://dx.doi.org/10.1038/s41398-021-01349-z

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