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Cancer-associated fibroblast-secreted exosomal miR-423-5p promotes chemotherapy resistance in prostate cancer by targeting GREM2 through the TGF-β signaling pathway

Therapeutic failure in prostate cancer (PC) is believed to result from its unusually invasive and metastatic nature. Cancer-associated fibroblasts (CAFs) are essential in the tumor microenvironment. We intended to study the role of CAF-derived exosomes in the context of PC and the potential regulato...

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Detalles Bibliográficos
Autores principales:	Shan, Guang, Gu, Juan, Zhou, Daoping, Li, Lingxun, Cheng, Wei, Wang, Yueping, Tang, Tian, Wang, Xuedong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8080786/ https://www.ncbi.nlm.nih.gov/pubmed/33144675 http://dx.doi.org/10.1038/s12276-020-0431-z

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