Spermidine attenuates bleomycin-induced lung fibrosis by inducing autophagy and inhibiting endoplasmic reticulum stress (ERS)-induced cell death in mice

Spermidine is an endogenous biological polyamine that plays various longevity-extending roles and exerts antioxidative, antiaging, and cell growth-promoting effects. We previously reported that spermidine levels were significantly reduced in idiopathic pulmonary fibrosis (IPF) of the lung. The prese...

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Detalles Bibliográficos
Autores principales: Baek, Ae Rin, Hong, Jisu, Song, Ki Sung, Jang, An Soo, Kim, Do Jin, Chin, Su Sie, Park, Sung Woo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8080799/
https://www.ncbi.nlm.nih.gov/pubmed/33318630
http://dx.doi.org/10.1038/s12276-020-00545-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8080799/
https://www.ncbi.nlm.nih.gov/pubmed/33318630
http://dx.doi.org/10.1038/s12276-020-00545-z

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