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DYRK2 controls a key regulatory network in chronic myeloid leukemia stem cells

Chronic myeloid leukemia is a hematological cancer driven by the oncoprotein BCR-ABL1, and lifelong treatment with tyrosine kinase inhibitors extends patient survival to nearly the life expectancy of the general population. Despite advances in the development of more potent tyrosine kinase inhibitor...

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Detalles Bibliográficos
Autores principales: Park, Chun Shik, Lacorazza, H. Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8080801/
https://www.ncbi.nlm.nih.gov/pubmed/33067577
http://dx.doi.org/10.1038/s12276-020-00515-5