Cargando…

Femtosecond laser micromachining of an optofluidics-based monolithic whispering-gallery mode resonator coupled to a suspended waveguide

A monolithic lab-on-a-chip fabricated by femtosecond laser micromachining capable of label-free biosensing is reported. The device is entirely made of fused silica, and consists of a microdisk resonator integrated inside a microfluidic channel. Whispering gallery modes are excited by the evanescent...

Descripción completa

Detalles Bibliográficos
Autores principales: Maia, João M., Amorim, Vítor A., Viveiros, Duarte, Marques, P. V. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8080832/
https://www.ncbi.nlm.nih.gov/pubmed/33911152
http://dx.doi.org/10.1038/s41598-021-88682-x
_version_ 1783685520360996864
author Maia, João M.
Amorim, Vítor A.
Viveiros, Duarte
Marques, P. V. S.
author_facet Maia, João M.
Amorim, Vítor A.
Viveiros, Duarte
Marques, P. V. S.
author_sort Maia, João M.
collection PubMed
description A monolithic lab-on-a-chip fabricated by femtosecond laser micromachining capable of label-free biosensing is reported. The device is entirely made of fused silica, and consists of a microdisk resonator integrated inside a microfluidic channel. Whispering gallery modes are excited by the evanescent field of a circular suspended waveguide, also incorporated within the channel. Thermal annealing is performed to decrease the surface roughness of the microstructures to a nanometric scale, thereby reducing intrinsic losses and maximizing the Q-factor. Further, thermally-induced morphing is used to position, with submicrometric precision, the suspended waveguide tangent to the microresonator to enhance the spatial overlap between the evanescent field of both optical modes. With this fabrication method and geometry, the alignment between the waveguide and the resonator is robust and guaranteed at all instances. A maximum sensitivity of 121.5 nm/RIU was obtained at a refractive index of 1.363, whereas near the refractive index range of water-based solutions the sensitivity is 40 nm/RIU. A high Q-factor of 10(5) is kept throughout the entire measurement range.
format Online
Article
Text
id pubmed-8080832
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Nature Publishing Group UK
record_format MEDLINE/PubMed
spelling pubmed-80808322021-04-30 Femtosecond laser micromachining of an optofluidics-based monolithic whispering-gallery mode resonator coupled to a suspended waveguide Maia, João M. Amorim, Vítor A. Viveiros, Duarte Marques, P. V. S. Sci Rep Article A monolithic lab-on-a-chip fabricated by femtosecond laser micromachining capable of label-free biosensing is reported. The device is entirely made of fused silica, and consists of a microdisk resonator integrated inside a microfluidic channel. Whispering gallery modes are excited by the evanescent field of a circular suspended waveguide, also incorporated within the channel. Thermal annealing is performed to decrease the surface roughness of the microstructures to a nanometric scale, thereby reducing intrinsic losses and maximizing the Q-factor. Further, thermally-induced morphing is used to position, with submicrometric precision, the suspended waveguide tangent to the microresonator to enhance the spatial overlap between the evanescent field of both optical modes. With this fabrication method and geometry, the alignment between the waveguide and the resonator is robust and guaranteed at all instances. A maximum sensitivity of 121.5 nm/RIU was obtained at a refractive index of 1.363, whereas near the refractive index range of water-based solutions the sensitivity is 40 nm/RIU. A high Q-factor of 10(5) is kept throughout the entire measurement range. Nature Publishing Group UK 2021-04-28 /pmc/articles/PMC8080832/ /pubmed/33911152 http://dx.doi.org/10.1038/s41598-021-88682-x Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Maia, João M.
Amorim, Vítor A.
Viveiros, Duarte
Marques, P. V. S.
Femtosecond laser micromachining of an optofluidics-based monolithic whispering-gallery mode resonator coupled to a suspended waveguide
title Femtosecond laser micromachining of an optofluidics-based monolithic whispering-gallery mode resonator coupled to a suspended waveguide
title_full Femtosecond laser micromachining of an optofluidics-based monolithic whispering-gallery mode resonator coupled to a suspended waveguide
title_fullStr Femtosecond laser micromachining of an optofluidics-based monolithic whispering-gallery mode resonator coupled to a suspended waveguide
title_full_unstemmed Femtosecond laser micromachining of an optofluidics-based monolithic whispering-gallery mode resonator coupled to a suspended waveguide
title_short Femtosecond laser micromachining of an optofluidics-based monolithic whispering-gallery mode resonator coupled to a suspended waveguide
title_sort femtosecond laser micromachining of an optofluidics-based monolithic whispering-gallery mode resonator coupled to a suspended waveguide
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8080832/
https://www.ncbi.nlm.nih.gov/pubmed/33911152
http://dx.doi.org/10.1038/s41598-021-88682-x
work_keys_str_mv AT maiajoaom femtosecondlasermicromachiningofanoptofluidicsbasedmonolithicwhisperinggallerymoderesonatorcoupledtoasuspendedwaveguide
AT amorimvitora femtosecondlasermicromachiningofanoptofluidicsbasedmonolithicwhisperinggallerymoderesonatorcoupledtoasuspendedwaveguide
AT viveirosduarte femtosecondlasermicromachiningofanoptofluidicsbasedmonolithicwhisperinggallerymoderesonatorcoupledtoasuspendedwaveguide
AT marquespvs femtosecondlasermicromachiningofanoptofluidicsbasedmonolithicwhisperinggallerymoderesonatorcoupledtoasuspendedwaveguide