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Surveillance of the Second Wave of COVID-19 in Europe: Longitudinal Trend Analyses

BACKGROUND: The COVID-19 pandemic has severely impacted Europe, resulting in a high caseload and deaths that varied by country. The second wave of the COVID-19 pandemic has breached the borders of Europe. Public health surveillance is necessary to inform policy and guide leaders. OBJECTIVE: This stu...

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Autores principales: Post, Lori, Culler, Kasen, Moss, Charles B, Murphy, Robert L, Achenbach, Chad J, Ison, Michael G, Resnick, Danielle, Singh, Lauren Nadya, White, Janine, Boctor, Michael J, Welch, Sarah B, Oehmke, James Francis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: JMIR Publications 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8080962/
https://www.ncbi.nlm.nih.gov/pubmed/33818391
http://dx.doi.org/10.2196/25695
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author Post, Lori
Culler, Kasen
Moss, Charles B
Murphy, Robert L
Achenbach, Chad J
Ison, Michael G
Resnick, Danielle
Singh, Lauren Nadya
White, Janine
Boctor, Michael J
Welch, Sarah B
Oehmke, James Francis
author_facet Post, Lori
Culler, Kasen
Moss, Charles B
Murphy, Robert L
Achenbach, Chad J
Ison, Michael G
Resnick, Danielle
Singh, Lauren Nadya
White, Janine
Boctor, Michael J
Welch, Sarah B
Oehmke, James Francis
author_sort Post, Lori
collection PubMed
description BACKGROUND: The COVID-19 pandemic has severely impacted Europe, resulting in a high caseload and deaths that varied by country. The second wave of the COVID-19 pandemic has breached the borders of Europe. Public health surveillance is necessary to inform policy and guide leaders. OBJECTIVE: This study aimed to provide advanced surveillance metrics for COVID-19 transmission that account for weekly shifts in the pandemic, speed, acceleration, jerk, and persistence, to better understand countries at risk for explosive growth and those that are managing the pandemic effectively. METHODS: We performed a longitudinal trend analysis and extracted 62 days of COVID-19 data from public health registries. We used an empirical difference equation to measure the daily number of cases in Europe as a function of the prior number of cases, the level of testing, and weekly shift variables based on a dynamic panel model that was estimated using the generalized method of moments approach by implementing the Arellano-Bond estimator in R. RESULTS: New COVID-19 cases slightly decreased from 158,741 (week 1, January 4-10, 2021) to 152,064 (week 2, January 11-17, 2021), and cumulative cases increased from 22,507,271 (week 1) to 23,890,761 (week 2), with a weekly increase of 1,383,490 between January 10 and January 17. France, Germany, Italy, Spain, and the United Kingdom had the largest 7-day moving averages for new cases during week 1. During week 2, the 7-day moving average for France and Spain increased. From week 1 to week 2, the speed decreased (37.72 to 33.02 per 100,000), acceleration decreased (0.39 to –0.16 per 100,000), and jerk increased (–1.30 to 1.37 per 100,000). CONCLUSIONS: The United Kingdom, Spain, and Portugal, in particular, are at risk for a rapid expansion in COVID-19 transmission. An examination of the European region suggests that there was a decrease in the COVID-19 caseload between January 4 and January 17, 2021. Unfortunately, the rates of jerk, which were negative for Europe at the beginning of the month, reversed course and became positive, despite decreases in speed and acceleration. Finally, the 7-day persistence rate was higher during week 2 than during week 1. These measures indicate that the second wave of the pandemic may be subsiding, but some countries remain at risk for new outbreaks and increased transmission in the absence of rapid policy responses.
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spelling pubmed-80809622021-05-06 Surveillance of the Second Wave of COVID-19 in Europe: Longitudinal Trend Analyses Post, Lori Culler, Kasen Moss, Charles B Murphy, Robert L Achenbach, Chad J Ison, Michael G Resnick, Danielle Singh, Lauren Nadya White, Janine Boctor, Michael J Welch, Sarah B Oehmke, James Francis JMIR Public Health Surveill Original Paper BACKGROUND: The COVID-19 pandemic has severely impacted Europe, resulting in a high caseload and deaths that varied by country. The second wave of the COVID-19 pandemic has breached the borders of Europe. Public health surveillance is necessary to inform policy and guide leaders. OBJECTIVE: This study aimed to provide advanced surveillance metrics for COVID-19 transmission that account for weekly shifts in the pandemic, speed, acceleration, jerk, and persistence, to better understand countries at risk for explosive growth and those that are managing the pandemic effectively. METHODS: We performed a longitudinal trend analysis and extracted 62 days of COVID-19 data from public health registries. We used an empirical difference equation to measure the daily number of cases in Europe as a function of the prior number of cases, the level of testing, and weekly shift variables based on a dynamic panel model that was estimated using the generalized method of moments approach by implementing the Arellano-Bond estimator in R. RESULTS: New COVID-19 cases slightly decreased from 158,741 (week 1, January 4-10, 2021) to 152,064 (week 2, January 11-17, 2021), and cumulative cases increased from 22,507,271 (week 1) to 23,890,761 (week 2), with a weekly increase of 1,383,490 between January 10 and January 17. France, Germany, Italy, Spain, and the United Kingdom had the largest 7-day moving averages for new cases during week 1. During week 2, the 7-day moving average for France and Spain increased. From week 1 to week 2, the speed decreased (37.72 to 33.02 per 100,000), acceleration decreased (0.39 to –0.16 per 100,000), and jerk increased (–1.30 to 1.37 per 100,000). CONCLUSIONS: The United Kingdom, Spain, and Portugal, in particular, are at risk for a rapid expansion in COVID-19 transmission. An examination of the European region suggests that there was a decrease in the COVID-19 caseload between January 4 and January 17, 2021. Unfortunately, the rates of jerk, which were negative for Europe at the beginning of the month, reversed course and became positive, despite decreases in speed and acceleration. Finally, the 7-day persistence rate was higher during week 2 than during week 1. These measures indicate that the second wave of the pandemic may be subsiding, but some countries remain at risk for new outbreaks and increased transmission in the absence of rapid policy responses. JMIR Publications 2021-04-28 /pmc/articles/PMC8080962/ /pubmed/33818391 http://dx.doi.org/10.2196/25695 Text en ©Lori Post, Kasen Culler, Charles B Moss, Robert L Murphy, Chad J Achenbach, Michael G Ison, Danielle Resnick, Lauren Nadya Singh, Janine White, Michael J Boctor, Sarah B Welch, James Francis Oehmke. Originally published in JMIR Public Health and Surveillance (https://publichealth.jmir.org), 28.04.2021. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in JMIR Public Health and Surveillance, is properly cited. The complete bibliographic information, a link to the original publication on https://publichealth.jmir.org, as well as this copyright and license information must be included.
spellingShingle Original Paper
Post, Lori
Culler, Kasen
Moss, Charles B
Murphy, Robert L
Achenbach, Chad J
Ison, Michael G
Resnick, Danielle
Singh, Lauren Nadya
White, Janine
Boctor, Michael J
Welch, Sarah B
Oehmke, James Francis
Surveillance of the Second Wave of COVID-19 in Europe: Longitudinal Trend Analyses
title Surveillance of the Second Wave of COVID-19 in Europe: Longitudinal Trend Analyses
title_full Surveillance of the Second Wave of COVID-19 in Europe: Longitudinal Trend Analyses
title_fullStr Surveillance of the Second Wave of COVID-19 in Europe: Longitudinal Trend Analyses
title_full_unstemmed Surveillance of the Second Wave of COVID-19 in Europe: Longitudinal Trend Analyses
title_short Surveillance of the Second Wave of COVID-19 in Europe: Longitudinal Trend Analyses
title_sort surveillance of the second wave of covid-19 in europe: longitudinal trend analyses
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8080962/
https://www.ncbi.nlm.nih.gov/pubmed/33818391
http://dx.doi.org/10.2196/25695
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