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Impact of the N501Y substitution of SARS-CoV-2 Spike on neutralizing monoclonal antibodies targeting diverse epitopes

The emergence and rapid spread of the B.1.1.7 lineage (VOC-202012/01) SARS-CoV-2 variant has aroused global concern. The N501Y substitution is the only mutation in the interface between the RBD of B.1.1.7 and ACE2, raising concerns that its recognition by neutralizing antibodies may be affected. Her...

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Detalles Bibliográficos
Autores principales:	Cheng, Lin, Song, Shuo, Zhou, Bing, Ge, Xiangyang, Yu, Jiazhen, Zhang, Mingxia, Ju, Bin, Zhang, Zheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Short Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8081001/ https://www.ncbi.nlm.nih.gov/pubmed/33910569 http://dx.doi.org/10.1186/s12985-021-01554-8

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