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Epithelial–immune cell interplay in primary Sjögren syndrome salivary gland pathogenesis

In primary Sjögren syndrome (pSS), the function of the salivary glands is often considerably reduced. Multiple innate immune pathways are likely dysregulated in the salivary gland epithelium in pSS, including the nuclear factor-κB pathway, the inflammasome and interferon signalling. The ductal cells...

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Detalles Bibliográficos
Autores principales: Verstappen, Gwenny M., Pringle, Sarah, Bootsma, Hendrika, Kroese, Frans G. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8081003/
https://www.ncbi.nlm.nih.gov/pubmed/33911236
http://dx.doi.org/10.1038/s41584-021-00605-2