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In vitro Demonstration of Melanoma Metastasis in Lymph Nodes of Prepared Specimens Using a Light-emitting Diode-based Multispectral Photoacoustic Ultrasound Imaging System
Although an excellent photoacoustic (PA) ultrasound method has been reported for the evaluation of lymph node melanoma metastasis in animal experiments, it remains to be evaluated in clinical trials. Recently, we performed PA ultrasound assessment using light-emitting diodes to detect metastatic mel...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer - Medknow
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8081111/ https://www.ncbi.nlm.nih.gov/pubmed/34084717 http://dx.doi.org/10.4103/JMU.JMU_121_19 |
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author | Ohta, Tomoyuki Shirakawa, Takako Okada, Shinya Ishii, Naohiro Kiryu, Shigeru |
author_facet | Ohta, Tomoyuki Shirakawa, Takako Okada, Shinya Ishii, Naohiro Kiryu, Shigeru |
author_sort | Ohta, Tomoyuki |
collection | PubMed |
description | Although an excellent photoacoustic (PA) ultrasound method has been reported for the evaluation of lymph node melanoma metastasis in animal experiments, it remains to be evaluated in clinical trials. Recently, we performed PA ultrasound assessment using light-emitting diodes to detect metastatic melanoma in the lymph nodes of specimens prepared for microscopic examination. The PA effect was not obvious in amelanotic melanoma, but was seen in melanotic melanoma by PA imaging (PAI) and histopathological correlation in cases of primary melanotic melanoma accompanied by metastatic lymph nodes, including the coexistence of amelanotic melanoma and melanotic melanoma. Clinical workup should be performed with not only PAI but also conventional ultrasonography in cases with metastasis related to amelanotic transformation, which would likely be missed by PAI alone. |
format | Online Article Text |
id | pubmed-8081111 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Wolters Kluwer - Medknow |
record_format | MEDLINE/PubMed |
spelling | pubmed-80811112021-06-02 In vitro Demonstration of Melanoma Metastasis in Lymph Nodes of Prepared Specimens Using a Light-emitting Diode-based Multispectral Photoacoustic Ultrasound Imaging System Ohta, Tomoyuki Shirakawa, Takako Okada, Shinya Ishii, Naohiro Kiryu, Shigeru J Med Ultrasound Case Report Although an excellent photoacoustic (PA) ultrasound method has been reported for the evaluation of lymph node melanoma metastasis in animal experiments, it remains to be evaluated in clinical trials. Recently, we performed PA ultrasound assessment using light-emitting diodes to detect metastatic melanoma in the lymph nodes of specimens prepared for microscopic examination. The PA effect was not obvious in amelanotic melanoma, but was seen in melanotic melanoma by PA imaging (PAI) and histopathological correlation in cases of primary melanotic melanoma accompanied by metastatic lymph nodes, including the coexistence of amelanotic melanoma and melanotic melanoma. Clinical workup should be performed with not only PAI but also conventional ultrasonography in cases with metastasis related to amelanotic transformation, which would likely be missed by PAI alone. Wolters Kluwer - Medknow 2020-05-12 /pmc/articles/PMC8081111/ /pubmed/34084717 http://dx.doi.org/10.4103/JMU.JMU_121_19 Text en Copyright: © 2020 Journal of Medical Ultrasound https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. |
spellingShingle | Case Report Ohta, Tomoyuki Shirakawa, Takako Okada, Shinya Ishii, Naohiro Kiryu, Shigeru In vitro Demonstration of Melanoma Metastasis in Lymph Nodes of Prepared Specimens Using a Light-emitting Diode-based Multispectral Photoacoustic Ultrasound Imaging System |
title | In vitro Demonstration of Melanoma Metastasis in Lymph Nodes of Prepared Specimens Using a Light-emitting Diode-based Multispectral Photoacoustic Ultrasound Imaging System |
title_full | In vitro Demonstration of Melanoma Metastasis in Lymph Nodes of Prepared Specimens Using a Light-emitting Diode-based Multispectral Photoacoustic Ultrasound Imaging System |
title_fullStr | In vitro Demonstration of Melanoma Metastasis in Lymph Nodes of Prepared Specimens Using a Light-emitting Diode-based Multispectral Photoacoustic Ultrasound Imaging System |
title_full_unstemmed | In vitro Demonstration of Melanoma Metastasis in Lymph Nodes of Prepared Specimens Using a Light-emitting Diode-based Multispectral Photoacoustic Ultrasound Imaging System |
title_short | In vitro Demonstration of Melanoma Metastasis in Lymph Nodes of Prepared Specimens Using a Light-emitting Diode-based Multispectral Photoacoustic Ultrasound Imaging System |
title_sort | in vitro demonstration of melanoma metastasis in lymph nodes of prepared specimens using a light-emitting diode-based multispectral photoacoustic ultrasound imaging system |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8081111/ https://www.ncbi.nlm.nih.gov/pubmed/34084717 http://dx.doi.org/10.4103/JMU.JMU_121_19 |
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