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Successful medical management of fungal infective endocarditis post VSD closure
Fungal infective endocarditis (IE) is uncommon in postoperative cardiac surgical patients. The fungal IE accounts for 1.3%–6.8% of all IE cases and is considered the most severe form with a mortality rate as high as 45%–50%. There are various predisposing factors for fungal IE which include congenit...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer - Medknow
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8081123/ https://www.ncbi.nlm.nih.gov/pubmed/33938843 http://dx.doi.org/10.4103/aca.ACA_33_19 |
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author | Gourav, Kalla Krishna Prasad Mandal, Banashree Mishra, Anand Kumar Nayanar, V Krishna Narayanan |
author_facet | Gourav, Kalla Krishna Prasad Mandal, Banashree Mishra, Anand Kumar Nayanar, V Krishna Narayanan |
author_sort | Gourav, Kalla Krishna Prasad |
collection | PubMed |
description | Fungal infective endocarditis (IE) is uncommon in postoperative cardiac surgical patients. The fungal IE accounts for 1.3%–6.8% of all IE cases and is considered the most severe form with a mortality rate as high as 45%–50%. There are various predisposing factors for fungal IE which include congenital heart defects, cardiac interventions like pacemaker insertion, degenerative valvular heart diseases, long-term use of broad-spectrum antimicrobial therapy, and long-term use of central venous. Mortality can reach up to 100% without specific treatment. Definitive therapy necessitates surgical debridement of vegetations/mass/abscess followed by long-term treatment with antifungal agents in patients who have symptoms of heart failure despite optimum medical management. We, hereby, report a case of fungal IE which occurred after the closure of a ventricular septal defect and was treated successfully with liposomal amphotericin B. |
format | Online Article Text |
id | pubmed-8081123 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Wolters Kluwer - Medknow |
record_format | MEDLINE/PubMed |
spelling | pubmed-80811232021-06-02 Successful medical management of fungal infective endocarditis post VSD closure Gourav, Kalla Krishna Prasad Mandal, Banashree Mishra, Anand Kumar Nayanar, V Krishna Narayanan Ann Card Anaesth Case Report Fungal infective endocarditis (IE) is uncommon in postoperative cardiac surgical patients. The fungal IE accounts for 1.3%–6.8% of all IE cases and is considered the most severe form with a mortality rate as high as 45%–50%. There are various predisposing factors for fungal IE which include congenital heart defects, cardiac interventions like pacemaker insertion, degenerative valvular heart diseases, long-term use of broad-spectrum antimicrobial therapy, and long-term use of central venous. Mortality can reach up to 100% without specific treatment. Definitive therapy necessitates surgical debridement of vegetations/mass/abscess followed by long-term treatment with antifungal agents in patients who have symptoms of heart failure despite optimum medical management. We, hereby, report a case of fungal IE which occurred after the closure of a ventricular septal defect and was treated successfully with liposomal amphotericin B. Wolters Kluwer - Medknow 2021 2021-01-22 /pmc/articles/PMC8081123/ /pubmed/33938843 http://dx.doi.org/10.4103/aca.ACA_33_19 Text en Copyright: © 2021 Annals of Cardiac Anaesthesia https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. |
spellingShingle | Case Report Gourav, Kalla Krishna Prasad Mandal, Banashree Mishra, Anand Kumar Nayanar, V Krishna Narayanan Successful medical management of fungal infective endocarditis post VSD closure |
title | Successful medical management of fungal infective endocarditis post VSD closure |
title_full | Successful medical management of fungal infective endocarditis post VSD closure |
title_fullStr | Successful medical management of fungal infective endocarditis post VSD closure |
title_full_unstemmed | Successful medical management of fungal infective endocarditis post VSD closure |
title_short | Successful medical management of fungal infective endocarditis post VSD closure |
title_sort | successful medical management of fungal infective endocarditis post vsd closure |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8081123/ https://www.ncbi.nlm.nih.gov/pubmed/33938843 http://dx.doi.org/10.4103/aca.ACA_33_19 |
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