Cargando…

Successful medical management of fungal infective endocarditis post VSD closure

Fungal infective endocarditis (IE) is uncommon in postoperative cardiac surgical patients. The fungal IE accounts for 1.3%–6.8% of all IE cases and is considered the most severe form with a mortality rate as high as 45%–50%. There are various predisposing factors for fungal IE which include congenit...

Descripción completa

Detalles Bibliográficos
Autores principales: Gourav, Kalla Krishna Prasad, Mandal, Banashree, Mishra, Anand Kumar, Nayanar, V Krishna Narayanan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8081123/
https://www.ncbi.nlm.nih.gov/pubmed/33938843
http://dx.doi.org/10.4103/aca.ACA_33_19
_version_ 1783685572566450176
author Gourav, Kalla Krishna Prasad
Mandal, Banashree
Mishra, Anand Kumar
Nayanar, V Krishna Narayanan
author_facet Gourav, Kalla Krishna Prasad
Mandal, Banashree
Mishra, Anand Kumar
Nayanar, V Krishna Narayanan
author_sort Gourav, Kalla Krishna Prasad
collection PubMed
description Fungal infective endocarditis (IE) is uncommon in postoperative cardiac surgical patients. The fungal IE accounts for 1.3%–6.8% of all IE cases and is considered the most severe form with a mortality rate as high as 45%–50%. There are various predisposing factors for fungal IE which include congenital heart defects, cardiac interventions like pacemaker insertion, degenerative valvular heart diseases, long-term use of broad-spectrum antimicrobial therapy, and long-term use of central venous. Mortality can reach up to 100% without specific treatment. Definitive therapy necessitates surgical debridement of vegetations/mass/abscess followed by long-term treatment with antifungal agents in patients who have symptoms of heart failure despite optimum medical management. We, hereby, report a case of fungal IE which occurred after the closure of a ventricular septal defect and was treated successfully with liposomal amphotericin B.
format Online
Article
Text
id pubmed-8081123
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Wolters Kluwer - Medknow
record_format MEDLINE/PubMed
spelling pubmed-80811232021-06-02 Successful medical management of fungal infective endocarditis post VSD closure Gourav, Kalla Krishna Prasad Mandal, Banashree Mishra, Anand Kumar Nayanar, V Krishna Narayanan Ann Card Anaesth Case Report Fungal infective endocarditis (IE) is uncommon in postoperative cardiac surgical patients. The fungal IE accounts for 1.3%–6.8% of all IE cases and is considered the most severe form with a mortality rate as high as 45%–50%. There are various predisposing factors for fungal IE which include congenital heart defects, cardiac interventions like pacemaker insertion, degenerative valvular heart diseases, long-term use of broad-spectrum antimicrobial therapy, and long-term use of central venous. Mortality can reach up to 100% without specific treatment. Definitive therapy necessitates surgical debridement of vegetations/mass/abscess followed by long-term treatment with antifungal agents in patients who have symptoms of heart failure despite optimum medical management. We, hereby, report a case of fungal IE which occurred after the closure of a ventricular septal defect and was treated successfully with liposomal amphotericin B. Wolters Kluwer - Medknow 2021 2021-01-22 /pmc/articles/PMC8081123/ /pubmed/33938843 http://dx.doi.org/10.4103/aca.ACA_33_19 Text en Copyright: © 2021 Annals of Cardiac Anaesthesia https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Case Report
Gourav, Kalla Krishna Prasad
Mandal, Banashree
Mishra, Anand Kumar
Nayanar, V Krishna Narayanan
Successful medical management of fungal infective endocarditis post VSD closure
title Successful medical management of fungal infective endocarditis post VSD closure
title_full Successful medical management of fungal infective endocarditis post VSD closure
title_fullStr Successful medical management of fungal infective endocarditis post VSD closure
title_full_unstemmed Successful medical management of fungal infective endocarditis post VSD closure
title_short Successful medical management of fungal infective endocarditis post VSD closure
title_sort successful medical management of fungal infective endocarditis post vsd closure
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8081123/
https://www.ncbi.nlm.nih.gov/pubmed/33938843
http://dx.doi.org/10.4103/aca.ACA_33_19
work_keys_str_mv AT gouravkallakrishnaprasad successfulmedicalmanagementoffungalinfectiveendocarditispostvsdclosure
AT mandalbanashree successfulmedicalmanagementoffungalinfectiveendocarditispostvsdclosure
AT mishraanandkumar successfulmedicalmanagementoffungalinfectiveendocarditispostvsdclosure
AT nayanarvkrishnanarayanan successfulmedicalmanagementoffungalinfectiveendocarditispostvsdclosure