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Encapsulation of Recombinant MOMP in Extended-Releasing PLGA 85:15 Nanoparticles Confer Protective Immunity Against a Chlamydia muridarum Genital Challenge and Re-Challenge

Recently we reported the immune-potentiating capacity of a Chlamydia nanovaccine (PLGA-rMOMP) comprising rMOMP (recombinant major outer membrane protein) encapsulated in extended-releasing PLGA [poly (D, L-lactide-co-glycolide) (85:15)] nanoparticles. Here we hypothesized that PLGA-rMOMP would bolst...

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Detalles Bibliográficos
Autores principales: Sahu, Rajnish, Dixit, Saurabh, Verma, Richa, Duncan, Skyla A., Smith, Lula, Giambartolomei, Guillermo H., Singh, Shree R., Dennis, Vida A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8081181/
https://www.ncbi.nlm.nih.gov/pubmed/33936096
http://dx.doi.org/10.3389/fimmu.2021.660932

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