A novel preparative method for nanoparticle albumin-bound paclitaxel with high drug loading and its evaluation both in vitro and in vivo

We developed a novel preparative method for nanoparticle albumin-bound (nab) paclitaxel with high drug loading, which was based on improved paclitaxel solubility in polyethylene glycol (PEG) and self-assembly of paclitaxel in PEG with albumin powders into nanoparticles. That is, paclitaxel and PEG w...

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Detalles Bibliográficos
Autores principales: Gao, Yue, Nai, Jingxue, Yang, Zhenbo, Zhang, Jinbang, Ma, Siyu, Zhao, Yumei, Li, Hui, Li, Jiaxin, Yang, Yang, Yang, Meiyan, Wang, Yuli, Gong, Wei, Yu, Fanglin, Gao, Chunsheng, Li, Zhiping, Mei, Xingguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8081182/
https://www.ncbi.nlm.nih.gov/pubmed/33909691
http://dx.doi.org/10.1371/journal.pone.0250670

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