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A novel small molecule LLL12B inhibits STAT3 signaling and sensitizes ovarian cancer cell to paclitaxel and cisplatin

Ovarian cancer is the fifth most common cause of cancer deaths among American women. Platinum and taxane combination chemotherapy represents the first-line approach for ovarian cancer, but treatment success is often limited by chemoresistance. Therefore, it is necessary to find new drugs to sensitiz...

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Detalles Bibliográficos
Autores principales: Zhang, Ruijie, Yang, Xiaozhi, Roque, Dana M., Li, Chenglong, Lin, Jiayuh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8081214/
https://www.ncbi.nlm.nih.gov/pubmed/33909625
http://dx.doi.org/10.1371/journal.pone.0240145