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Accurate cancer phenotype prediction with AKLIMATE, a stacked kernel learner integrating multimodal genomic data and pathway knowledge
Advancements in sequencing have led to the proliferation of multi-omic profiles of human cells under different conditions and perturbations. In addition, many databases have amassed information about pathways and gene “signatures”—patterns of gene expression associated with specific cellular and phe...
Autores principales: | Uzunangelov, Vladislav, Wong, Christopher K., Stuart, Joshua M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8081343/ https://www.ncbi.nlm.nih.gov/pubmed/33861732 http://dx.doi.org/10.1371/journal.pcbi.1008878 |
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