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Classification of COVID-19 chest X-Ray and CT images using a type of dynamic CNN modification method

Understanding and classifying Chest X-Ray (CXR) and computerised tomography (CT) images are of great significance for COVID-19 diagnosis. The existing research on the classification for COVID-19 cases faces the challenges of data imbalance, insufficient generalisability, the lack of comparative stud...

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Detalles Bibliográficos
Autores principales: Jia, Guangyu, Lam, Hak-Keung, Xu, Yujia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8081579/
https://www.ncbi.nlm.nih.gov/pubmed/33971427
http://dx.doi.org/10.1016/j.compbiomed.2021.104425
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author Jia, Guangyu
Lam, Hak-Keung
Xu, Yujia
author_facet Jia, Guangyu
Lam, Hak-Keung
Xu, Yujia
author_sort Jia, Guangyu
collection PubMed
description Understanding and classifying Chest X-Ray (CXR) and computerised tomography (CT) images are of great significance for COVID-19 diagnosis. The existing research on the classification for COVID-19 cases faces the challenges of data imbalance, insufficient generalisability, the lack of comparative study, etc. To address these problems, this paper proposes a type of modified MobileNet to classify COVID-19 CXR images and a modified ResNet architecture for CT image classification. In particular, a modification method of convolutional neural networks (CNN) is designed to solve the gradient vanishing problem and improve the classification performance through dynamically combining features in different layers of a CNN. The modified MobileNet is applied to the classification of COVID-19, Tuberculosis, viral pneumonia (with the exception of COVID-19), bacterial pneumonia and normal controls using CXR images. Also, the proposed modified ResNet is used for the classification of COVID-19, non-COVID-19 infections and normal controls using CT images. The results show that the proposed methods achieve 99.6% test accuracy on the five-category CXR image dataset and 99.3% test accuracy on the CT image dataset. Six advanced CNN architectures and two specific COVID-19 detection models, i.e., COVID-Net and COVIDNet-CT are used in comparative studies. Two benchmark datasets and a CXR image dataset which combines eight different CXR image sources are employed to evaluate the performance of the above models. The results show that the proposed methods outperform the comparative models in classification accuracy, sensitivity, and precision, which demonstrate their potential in computer-aided diagnosis for healthcare applications.
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spelling pubmed-80815792021-04-29 Classification of COVID-19 chest X-Ray and CT images using a type of dynamic CNN modification method Jia, Guangyu Lam, Hak-Keung Xu, Yujia Comput Biol Med Article Understanding and classifying Chest X-Ray (CXR) and computerised tomography (CT) images are of great significance for COVID-19 diagnosis. The existing research on the classification for COVID-19 cases faces the challenges of data imbalance, insufficient generalisability, the lack of comparative study, etc. To address these problems, this paper proposes a type of modified MobileNet to classify COVID-19 CXR images and a modified ResNet architecture for CT image classification. In particular, a modification method of convolutional neural networks (CNN) is designed to solve the gradient vanishing problem and improve the classification performance through dynamically combining features in different layers of a CNN. The modified MobileNet is applied to the classification of COVID-19, Tuberculosis, viral pneumonia (with the exception of COVID-19), bacterial pneumonia and normal controls using CXR images. Also, the proposed modified ResNet is used for the classification of COVID-19, non-COVID-19 infections and normal controls using CT images. The results show that the proposed methods achieve 99.6% test accuracy on the five-category CXR image dataset and 99.3% test accuracy on the CT image dataset. Six advanced CNN architectures and two specific COVID-19 detection models, i.e., COVID-Net and COVIDNet-CT are used in comparative studies. Two benchmark datasets and a CXR image dataset which combines eight different CXR image sources are employed to evaluate the performance of the above models. The results show that the proposed methods outperform the comparative models in classification accuracy, sensitivity, and precision, which demonstrate their potential in computer-aided diagnosis for healthcare applications. Elsevier Ltd. 2021-07 2021-04-29 /pmc/articles/PMC8081579/ /pubmed/33971427 http://dx.doi.org/10.1016/j.compbiomed.2021.104425 Text en © 2021 Elsevier Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Jia, Guangyu
Lam, Hak-Keung
Xu, Yujia
Classification of COVID-19 chest X-Ray and CT images using a type of dynamic CNN modification method
title Classification of COVID-19 chest X-Ray and CT images using a type of dynamic CNN modification method
title_full Classification of COVID-19 chest X-Ray and CT images using a type of dynamic CNN modification method
title_fullStr Classification of COVID-19 chest X-Ray and CT images using a type of dynamic CNN modification method
title_full_unstemmed Classification of COVID-19 chest X-Ray and CT images using a type of dynamic CNN modification method
title_short Classification of COVID-19 chest X-Ray and CT images using a type of dynamic CNN modification method
title_sort classification of covid-19 chest x-ray and ct images using a type of dynamic cnn modification method
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8081579/
https://www.ncbi.nlm.nih.gov/pubmed/33971427
http://dx.doi.org/10.1016/j.compbiomed.2021.104425
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