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Total Flavonoids of Rhizoma Drynariae Restore the MMP/TIMP Balance in Models of Osteoarthritis by Inhibiting the Activation of the NF-κB and PI3K/AKT Pathways
Total flavonoids of Rhizoma Drynariae (TFRD) have been shown to have beneficial effects on osteoarthritis (OA) clinically, but the mechanisms have not been elucidated. In this study, we investigated the effect of TFRD on articular cartilage in an OA rat model established by the Hulth method and in S...
Autores principales: | Chen, Guang-Yao, Chen, Jia-Qi, Liu, Xiao-Yu, Xu, Yuan, Luo, Jing, Wang, Yi-Fei, Zhou, Tong-Liang, Yan, Ze-Ran, Zhou, Li, Tao, Qing-Wen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8081598/ https://www.ncbi.nlm.nih.gov/pubmed/33995548 http://dx.doi.org/10.1155/2021/6634837 |
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