Cargando…

Exploring the Role and Mechanism of pAMPKα-Mediated Dysregulation of Brf1 and RNA Pol III Genes

TF IIB-related factor 1 (Brf1) is a key transcription factor of RNA polymerase III (Pol III) genes. Our early studies have demonstrated that Brf1 and Pol III genes are epigenetically modulated by histone H3 phosphorylation. Here, we have further investigated the relationship of the abnormal expressi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wu, Teng, Zhang, Dongkun, Lin, Mingen, Yu, Lihong, Dai, Ting, Li, Shuai, Yu, Fenghai, Lu, Lei, Zheng, Liling, Zhong, Shuping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8081602/ https://www.ncbi.nlm.nih.gov/pubmed/33995823 http://dx.doi.org/10.1155/2021/5554932

Ejemplares similares

ROS Signaling-Mediated Novel Biological Targets: Brf1 and RNA Pol III Genes
por: Zheng, Liling, et al.
Publicado: (2021)

A Fbxo48 inhibitor prevents pAMPKα degradation and ameliorates insulin resistance
por: Liu, Yuan, et al.
Publicado: (2021)

Pirfenidone Is an Agonistic Ligand for PPARα and Improves NASH by Activation of SIRT1/LKB1/pAMPK
por: Sandoval‐Rodriguez, Ana, et al.
Publicado: (2020)

Distinct Plasma Immune Profile in ALS Implicates sTNFR-II in pAMPK/Leptin Homeostasis
por: Picher-Martel, Vincent, et al.
Publicado: (2023)

Mitogen- and Stress-Activated Protein Kinase 1 Mediates Alcohol-Upregulated Transcription of Brf1 and tRNA Genes to Cause Phenotypic Alteration
por: Lin, Mingen, et al.
Publicado: (2020)

Alcohol Intake and Abnormal Expression of Brf1 in Breast Cancer
por: Huang, Chenghao, et al.
Publicado: (2019)

RNA polymerase III transcription in cancer: the BRF2 connection
por: Cabarcas, Stephanie, et al.
Publicado: (2011)

Prognostic Implication of pAMPK Immunohistochemical Staining by Subcellular Location and Its Association with SMAD Protein Expression in Clear Cell Renal Cell Carcinoma
por: Jung, Minsun, et al.
Publicado: (2019)

Human Maf1 negatively regulates RNA Polymerase III transcription via the TFIIB family members Brf1 and Brf2
por: Rollins, Janet, et al.
Publicado: (2007)

The significance of Brf1 overexpression in human hepatocellular carcinoma
por: Zhong, Qian, et al.
Publicado: (2015)

Differential expression of the TFIIIB subunits Brf1 and Brf2 in cancer cells
por: Cabarcas, Stephanie, et al.
Publicado: (2008)

Diabetes Impairs the Vascular Recruitment of Normal Stem Cells by Oxidant Damage, Reversed by Increases in pAMPK, Heme Oxygenase-1, and Adiponectin
por: Sambuceti, Gianmario, et al.
Publicado: (2009)

Redox Signaling by the RNA Polymerase III TFIIB-Related Factor Brf2
por: Gouge, Jerome, et al.
Publicado: (2015)

Role of Brf1 interaction with ERα, and significance of its overexpression, in human breast cancer
por: Fang, Zeng, et al.
Publicado: (2017)

The L-4F mimetic peptide prevents insulin resistance through increased levels of HO-1, pAMPK, and pAKT in obese mice
por: Peterson, Stephen J., et al.
Publicado: (2009)

Bromine Pentafluoride BrF(5), the Formation of [BrF(6)](−) Salts, and the Stereochemical (In)activity of the Bromine Lone Pairs
por: Möbs, Martin, et al.
Publicado: (2022)

BRF1 mutations alter RNA polymerase III–dependent transcription and cause neurodevelopmental anomalies
por: Borck, Guntram, et al.
Publicado: (2015)

Vitamin D3 attenuates doxorubicin-induced senescence of human aortic endothelial cells by upregulation of IL-10 via the pAMPKα/Sirt1/Foxo3a signaling pathway
por: Chen, Lei, et al.
Publicado: (2021)

Targeting BRF2 in Cancer Using Repurposed Drugs
por: Rashidieh, Behnam, et al.
Publicado: (2021)

Enhancer SINEs Link Pol III to Pol II Transcription in Neurons
por: Policarpi, Cristina, et al.
Publicado: (2017)

Chromatin remodeling by Pol II primes efficient Pol III transcription
por: Yague-Sanz, Carlo, et al.
Publicado: (2023)

Genome-wide analyses of chromatin interactions after the loss of Pol I, Pol II, and Pol III
por: Jiang, Yongpeng, et al.
Publicado: (2020)

MALAT1/ mir-1-3p mediated BRF2 expression promotes HCC progression via inhibiting the LKB1/AMPK signaling pathway
por: Li, Guang-Zhen, et al.
Publicado: (2023)

New tricks for an old dog: Brf2-dependent RNA Polymerase III transcription in oxidative stress and cancer
por: Gouge, Jerome, et al.
Publicado: (2017)

BRF1 accelerates prostate tumourigenesis and perturbs immune infiltration
por: Loveridge, Carolyn J., et al.
Publicado: (2019)

A novel dipeptide from potato protein hydrolysate augments the effects of exercise training against high-fat diet-induced damages in senescence-accelerated mouse-prone 8 by boosting pAMPK / SIRT1/ PGC-1α/ pFOXO3 pathway
por: Asokan, Shibu Marthandam, et al.
Publicado: (2020)

Correction: BRF1 accelerates prostate tumourigenesis and perturbs immune infiltration
por: Loveridge, Carolyn J., et al.
Publicado: (2019)

Silencing of BRF2 inhibits the growth and metastasis of lung cancer cells
por: Bian, Yuan, et al.
Publicado: (2020)

BRF Negatively Regulates Thermotolerance Defect of fes1a in Arabidopsis
por: Fu, Can, et al.
Publicado: (2020)

The TFIIE-related Rpc82 subunit of RNA polymerase III interacts with the TFIIB-related transcription factor Brf1 and the polymerase cleft for transcription initiation
por: Khoo, Seok-Kooi, et al.
Publicado: (2018)

Brf1 loss and not overexpression disrupts tissues homeostasis in the intestine, liver and pancreas
por: Liko, Dritan, et al.
Publicado: (2019)

It’s Sno’ing on Pol III at nuclear pores
por: Maraia, Richard J, et al.
Publicado: (2013)

Pol II and its associated epigenetic marks are present at pol III-transcribed non-coding RNA genes
por: Barski, Artem, et al.
Publicado: (2010)

A meta-analysis of BRF2 as a prognostic biomarker in invasive breast carcinoma
por: Cabarcas-Petroski, Stephanie, et al.
Publicado: (2020)

Participation of TFIIIB Subunit Brf1 in Transcription Regulation in the Human Pathogen Leishmania major
por: Florencio-Martínez, Luis E., et al.
Publicado: (2021)

A novel BRF1 mutation in two middle-aged siblings with cerebellofaciodental syndrome
por: Zhao, Xin, et al.
Publicado: (2022)

RNA Processing Factors Swd2.2 and Sen1 Antagonize RNA Pol III-Dependent Transcription and the Localization of Condensin at Pol III Genes
por: Legros, Pénélope, et al.
Publicado: (2014)

Centromeric Localization of Dispersed Pol III Genes in Fission Yeast
por: Iwasaki, Osamu, et al.
Publicado: (2010)

Neurogenic bladder and neuroendocrine abnormalities in Pol III-related leukodystrophy
por: Potic, Ana, et al.
Publicado: (2015)

Natural Selection, Crypt Fitness, and Pol III Dependency in the Intestine
por: Jadhav, Unmesh, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_3korcoffa082abb4i7tbq6n77a