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PD-L1 Improves Motor Function and Alleviates Neuropathic Pain in Male Mice After Spinal Cord Injury by Inhibiting MAPK Pathway
BACKGROUND: Traumatic spinal cord injury (SCI) causes severe motor dysfunction and persistent central neuropathic pain (Nep), which has not yet been effectively cured. Programmed cell death ligand-1 (PD-L1) is typically produced by cancer cells and contributes to the immune-suppressive in tumor micr...
Autores principales: | Kong, Fanqi, Sun, Kaiqiang, Zhu, Jian, Li, Fudong, Lin, Feng, Sun, Xiaofei, Luo, Xi, Ren, Changzhen, Lu, Lantao, Zhao, ShuJie, Sun, Jingchuan, Wang, Yuan, Shi, Jiangang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8081847/ https://www.ncbi.nlm.nih.gov/pubmed/33936116 http://dx.doi.org/10.3389/fimmu.2021.670646 |
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