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Endogenous hydrogen sulfide regulates xCT stability through persulfidation of OTUB1 at cysteine 91 in colon cancer cells
Increased xCT and transsulfuration pathway has been associated with metabolic reprogramming of colorectal cancer. However, the correlation between these 2 events and the underlying molecular mechanism remains obscure. xCT expression was determined in tissue microarrays of colorectal cancer. RNA sequ...
Autores principales: | Chen, Shanwen, Bu, Dingfang, Zhu, Jing, Yue, Taohua, Guo, Shihao, Wang, Xin, Pan, Yisheng, Liu, Yucun, Wang, Pengyuan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Neoplasia Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8081877/ https://www.ncbi.nlm.nih.gov/pubmed/33878705 http://dx.doi.org/10.1016/j.neo.2021.03.009 |
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