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Host specificity of Hepatocystis infection in short-nosed fruit bats (Cynopterus brachyotis) in Singapore

Haemosporidians infect a wide diversity of bat genera and species, yet little is known about their transmission cycles or epidemiology. Though several recent studies have focused on the genus Hepatocystis, an Old World parasite primarily infecting bats, monkeys, and squirrels, this group is still un...

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Autores principales: Low, Dolyce H.W., Hitch, Alan T., Skiles, Maggie M., Borthwick, Sophie A., Neves, Erica S., Lim, Zong Xian, Lee, Benjamin P.Y-H., Su, Yvonne C.F., Smith, Gavin J.D., Mendenhall, Ian H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8081878/
https://www.ncbi.nlm.nih.gov/pubmed/33948432
http://dx.doi.org/10.1016/j.ijppaw.2021.04.001
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author Low, Dolyce H.W.
Hitch, Alan T.
Skiles, Maggie M.
Borthwick, Sophie A.
Neves, Erica S.
Lim, Zong Xian
Lee, Benjamin P.Y-H.
Su, Yvonne C.F.
Smith, Gavin J.D.
Mendenhall, Ian H.
author_facet Low, Dolyce H.W.
Hitch, Alan T.
Skiles, Maggie M.
Borthwick, Sophie A.
Neves, Erica S.
Lim, Zong Xian
Lee, Benjamin P.Y-H.
Su, Yvonne C.F.
Smith, Gavin J.D.
Mendenhall, Ian H.
author_sort Low, Dolyce H.W.
collection PubMed
description Haemosporidians infect a wide diversity of bat genera and species, yet little is known about their transmission cycles or epidemiology. Though several recent studies have focused on the genus Hepatocystis, an Old World parasite primarily infecting bats, monkeys, and squirrels, this group is still understudied with little known about its transmission and molecular ecology. These parasites lack an asexual erythrocytic stage, making them unique from the Plasmodium vertebrate life cycle. In this study, we detected a prevalence of 31% of Hepatocystis in short-nosed fruit bats (Cynopterus brachyotis) in Singapore. Phylogenetic reconstruction with a partial cytochrome b sequence revealed a monophyletic group of Hepatocystis from C. brachyotis in Malaysia, Singapore, and Thailand. There was no relationship with infection and bat age, sex, location, body condition or monsoon season. The absence of this parasite in the five other bat species sampled in Singapore indicates this Hepatocystis species may be host restricted.
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spelling pubmed-80818782021-05-03 Host specificity of Hepatocystis infection in short-nosed fruit bats (Cynopterus brachyotis) in Singapore Low, Dolyce H.W. Hitch, Alan T. Skiles, Maggie M. Borthwick, Sophie A. Neves, Erica S. Lim, Zong Xian Lee, Benjamin P.Y-H. Su, Yvonne C.F. Smith, Gavin J.D. Mendenhall, Ian H. Int J Parasitol Parasites Wildl Regular Article Haemosporidians infect a wide diversity of bat genera and species, yet little is known about their transmission cycles or epidemiology. Though several recent studies have focused on the genus Hepatocystis, an Old World parasite primarily infecting bats, monkeys, and squirrels, this group is still understudied with little known about its transmission and molecular ecology. These parasites lack an asexual erythrocytic stage, making them unique from the Plasmodium vertebrate life cycle. In this study, we detected a prevalence of 31% of Hepatocystis in short-nosed fruit bats (Cynopterus brachyotis) in Singapore. Phylogenetic reconstruction with a partial cytochrome b sequence revealed a monophyletic group of Hepatocystis from C. brachyotis in Malaysia, Singapore, and Thailand. There was no relationship with infection and bat age, sex, location, body condition or monsoon season. The absence of this parasite in the five other bat species sampled in Singapore indicates this Hepatocystis species may be host restricted. Elsevier 2021-04-15 /pmc/articles/PMC8081878/ /pubmed/33948432 http://dx.doi.org/10.1016/j.ijppaw.2021.04.001 Text en © 2021 Published by Elsevier Ltd on behalf of Australian Society for Parasitology. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Regular Article
Low, Dolyce H.W.
Hitch, Alan T.
Skiles, Maggie M.
Borthwick, Sophie A.
Neves, Erica S.
Lim, Zong Xian
Lee, Benjamin P.Y-H.
Su, Yvonne C.F.
Smith, Gavin J.D.
Mendenhall, Ian H.
Host specificity of Hepatocystis infection in short-nosed fruit bats (Cynopterus brachyotis) in Singapore
title Host specificity of Hepatocystis infection in short-nosed fruit bats (Cynopterus brachyotis) in Singapore
title_full Host specificity of Hepatocystis infection in short-nosed fruit bats (Cynopterus brachyotis) in Singapore
title_fullStr Host specificity of Hepatocystis infection in short-nosed fruit bats (Cynopterus brachyotis) in Singapore
title_full_unstemmed Host specificity of Hepatocystis infection in short-nosed fruit bats (Cynopterus brachyotis) in Singapore
title_short Host specificity of Hepatocystis infection in short-nosed fruit bats (Cynopterus brachyotis) in Singapore
title_sort host specificity of hepatocystis infection in short-nosed fruit bats (cynopterus brachyotis) in singapore
topic Regular Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8081878/
https://www.ncbi.nlm.nih.gov/pubmed/33948432
http://dx.doi.org/10.1016/j.ijppaw.2021.04.001
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